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First accurate data on dynamic molecular aggregates in cells

First accurate data on dynamic molecular aggregates in cells
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United Kingdom , Aleks Reinhardt , Thorsten Hugel , Ritwick Sawakar , Nature Communications , University Of Cambridge , Department Of Chemistry , University Of Freiburg , Integrative Biological Signaling Studies , Supplementary Movies , Source Data ,

Hierarchical dynamics


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IMAGE: Researchers from Freiburg have been able to analyze the precise rate of signal transfer across multiple time scales.
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Credit: Graphic: Steffen Wolf
Consider for a moment a tree swaying in the wind. How long does it take for the movement of a twig to reach the trunk of the tree? How is this motion actually transmitted through the tree? Researchers at the University of Freiburg are transferring this kind of question to the analysis of proteins - which are the molecular machinery of cells. A team of researchers lead by Prof. Dr. Thorsten Hugel of the Institute of Physical Chemistry, and Dr. Steffen Wolf and Prof. Dr. Gerhard Stock of the Institute of Physics are investigating how the signals that cause structural changes in proteins travel from one site to another. They are also trying to determine how fast these mechanisms take place. Until now, researchers have been unable to analyze the precise rate of signal transfer because it i ....

Steffen Wolf , Thorsten Hugel , Collaborative Research Center , University Of Freiburg , Institute Of Physical Chemistry , Centre For Integrative Biological Signalling Studies , Research Unit , German Research Foundation , Institute Of Physics , Gerhard Stock Of The Institute Physics , Dynamic Organization Of Cellular Protein Machineries , Physical Chemistry , Gerhard Stock , Excellence Cluster , Integrative Biological Signalling Studies , Cellular Protein Machineries , ஸ்டெஃபென் ஓநாய் , முள் ஹுகல் , கூட்டு ஆராய்ச்சி மையம் , நிறுவனம் ஆஃப் உடல் வேதியியல் , ஆராய்ச்சி அலகு , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , நிறுவனம் ஆஃப் இயற்பியல் , ஜெர்ஹார்ட் ஸ்டாக் ஆஃப் தி நிறுவனம் இயற்பியல் , மாறும் ஆர்கநைஸேஶந் ஆஃப் செல்லுலார் ப்ரோடீந் எந்திரங்கள் , உடல் வேதியியல் ,