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Coronary Sinus Reducer an Option for Intractable Angina? - Vimarsana News

Coronary Sinus Reducer an Option for Intractable Angina?

A coronary sinus reducer met one of two primary endpoints by reducing refractory angina in the ORBITA-COSMIC trial, but not the second, improvement in perfusion.

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure - Vimarsana News

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure

AB-1002 is an investigational gene therapy for the treatment of adults with non-ischemic cardiomyopathy and New York Heart Association (NYHA) Class III heart failure symptoms1GenePHIT is a clinical trial to evaluate the safety and efficacy of the one-time administration of AB-1002 and will include the largest number...

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure Treatment - Vimarsana News

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure Treatment

Bayer AG and Asklepios BioPharmaceutical, Inc. (AskBio), a subsidiary of Bayer AG, have announced that the first patient has been randomized in GenePHIT (Gene PHosphatase Inhibition Therapy), a Phase II trial of AB-1002, also known as NAN-101, for the treatment of congestive heart failure (CHF).

AB-1002 Demonstrates Improvements for Congestive Heart Failure in First-in-Human Study - Vimarsana News

AB-1002 Demonstrates Improvements for Congestive Heart Failure in First-in-Human Study

Improvements were seen in left ventricular ejection fraction, NYHA Functional Class, and Minnesota Living with Heart Failure Questionnaire at 1-year post-dose.

AskBio Presents Preliminary Data from Phase 1 Trial of Gene Therapy for Congestive Heart Failure (CHF) at the 2023 American Heart Association Scientific Sessions - Vimarsana News

AskBio Presents Preliminary Data from Phase 1 Trial of Gene Therapy for Congestive Heart Failure (CHF) at the 2023 American Heart Association Scientific Sessions

/PRNewswire/ -- Asklepios BioPharmaceutical, Inc. (AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, today...