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Objectives To quantify mortality rates for patients successfully treated for hepatitis C in the era of interferon-free, direct acting antivirals and compare these rates with those of the general population.

Design Population based cohort study.

Setting British Columbia, Scotland, and England (England cohort consists of patients with cirrhosis only).

Participants 21 790 people who were successfully treated for hepatitis C in the era of interferon-free antivirals (2014-19). Participants were divided into three liver disease severity groups: people without cirrhosis (pre-cirrhosis), those with compensated cirrhosis, and those with end stage liver disease. Follow-up started 12 weeks after antiviral treatment completion and ended on date of death or 31 December 2019.

Main outcome measures Crude and age-sex standardised mortality rates, and standardised mortality ratio comparing the number of deaths with that of the general population, adjusting for age, sex, an ....

United Kingdom , William Irving , Data Access Request Service , Midlands Research Ethics Committee , Analysis Service , Research Foundation , National Cancer Registration , National Strategic Group For Viral , Services Plan , Behavioural Research Ethics Board , National Ambulatory Care Reporting System , Public Health Scotland , Privacy Public Benefit Panel For Health , Bc Vital Statistics Agency , Bc Vital Statistics Agency Death Registry , Tissue Data Access Committee , University Of British Columbia , Bc Centre For Disease , Gilead Sciences , Office For National Statistics , World Health Organization , Research United Kingdom England , British Columbia , Medical Services Plan , Discharge Abstracts Dataset , Statistics Agency Death ,