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Health outcomes after myocardial infarction: A population study of 56 million people in England

Using hospital records of 34 million adults admitted to hospitals in England, Marlous Hall and team examine the long-term risk of major health outcomes following myocardial infarction. ....

United Kingdom , United States , South Africa , Northern Ireland , Andrep Kengne , Charlotte Sturley , Daiichi Sankyo , Quality Indicator Committee , United Kingdom Phenotype Library , University Of Leeds , National Health Service , International Classification Of Disease , Leeds Analytic Secure Environment For Research , Clinical Research Training Fellowship , Raisio Group , Health Data Research United Kingdom , Alan Turing Institute , Boston Scientific , United Kingdom Myocardial Ischaemia National Audit Project , Indicator Advisory Committee , England Data Access Request Service , Office Of Population Censuses , British Heart Foundation , Wellcome Trust Sir Henry Postdoctoral Fellowship , Office For National Statistics , African Medical Research Council ,

Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study

Objectives To quantify mortality rates for patients successfully treated for hepatitis C in the era of interferon-free, direct acting antivirals and compare these rates with those of the general population.

Design Population based cohort study.

Setting British Columbia, Scotland, and England (England cohort consists of patients with cirrhosis only).

Participants 21 790 people who were successfully treated for hepatitis C in the era of interferon-free antivirals (2014-19). Participants were divided into three liver disease severity groups: people without cirrhosis (pre-cirrhosis), those with compensated cirrhosis, and those with end stage liver disease. Follow-up started 12 weeks after antiviral treatment completion and ended on date of death or 31 December 2019.

Main outcome measures Crude and age-sex standardised mortality rates, and standardised mortality ratio comparing the number of deaths with that of the general population, adjusting for age, sex, an ....

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Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study

Using data from the WHO ISARIC CCP-UK cohort, Dr. Lance Turtle and colleagues report on the outcome of COVID-19 in immunocompromised patients that are hospitalised. ....

United Kingdom , Glasgow City , City Of , Oxford Immunotech , Daiichi Sankyo , Chiesi Farmaceutici , Eli Lilly , Digital Data Access Request Service , Scotlanda Research Ethics Committee Ref , Oxfordc Research Ethics Committee , Scientist Office , Connectivity National Core Study , Material Access Committee , Zoonotic Infections At University Of Liverpool , Office Of National Statistics , University Of Oxford , United Kingdom Research , Health Protection Research Unit , Research Electronic Data Capture Redcap , Liverpool Experimental Cancer Medicine Centre , Liverpool School Of Tropical Medicine , Health Data Research United Kingdom , Office For National Statistics , Infections At Imperial College London , United Kingdom Scientific Advisory Group For Emergencies , Biomedical Research Centre At Imperial College London ,

Report urges more data sharing between NHS and private healthcare

Report urges more data sharing between NHS and private healthcare
ukauthority.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ukauthority.com Daily Mail and Mail on Sunday newspapers.

James Austin , Jon Fistein , Ian Paterson , Data Alignment Programme , Digital Data Access Request Service , Healthcare Information Network , Acute Data Alignment Programme , Private Healthcare Information Network , Data Access Request Service , Social Care Jeremy Hunt ,

Predicting major complications in patients undergoing laparoscopic and open hysterectomy for benign indications

Background: Hysterectomy, the most common gynecological operation, requires surgeons to counsel women about their operative risks. We aimed to develop and validate multivariable logistic regression models to predict major complications of laparoscopic or abdominal hysterectomy for benign conditions.

Methods: We obtained routinely collected health administrative data from the English National Health Service (NHS) from 2011 to 2018. We defined major complications based on core outcomes for postoperative complications including ureteric, gastrointestinal and vascular injury, and wound complications. We specified 11 predictors a priori. We used internal–external cross-validation to evaluate discrimination and calibration across 7 NHS regions in the development cohort. We validated the final models using data from an additional NHS region.

Results: We found that major complications occurred in 4.4% (3037/68 599) of laparoscopic and 4.9% (6201/125 971) of abdominal hysterecto ....

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