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The study ‘One to Three’ will compare the treatment completion of daily dose of Rifapentine and Isoniazid for a month (1HP) to the weekly dose of Rifapentine and Isoniazid for three months (3HP) in persons living with HIV in Pune.
The 18-month study was undertaken by researchers from B J Government Medical College (BJGMC) and Johns Hopkins University (JHU) to assess the WHO-recommended 3HP regime among People Living with HIV/AIDS (PLHIV), children living with HIV and child contacts of pulmonary TB patients.
Tuberculosis is caused due to under-nourishment, HIV, alcohol, smoking and diabetes. This ailment disproportionately affects the financially marginalised sections of the society, and the stigma associated with this disease lead to underreporting and underdiagnosis.