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Potential biomarker found for lung disease in scleroderma patients


Potential biomarker found for lung disease in scleroderma patients
The finding will indicate how aggressively physicians should treat patients with the associated condition.
Researchers have discovered a protein that may predict disease severity for a lung condition that often proves fatal to patients with scleroderma.
The recent study, published in
“Despite interstitial lung disease being the leading cause of death among scleroderma patients, there are very few markers that predict progression of the disease,” said John Varga, M.D., a corresponding author of the paper, chief of the Michigan Medicine Division of Rheumatology and associate director of the U-M Scleroderma Program. “CTRP9 is an entirely novel biomarker that has never been implicated in scleroderma. It will help physicians predict the course of the disease and identify those patients who would not need to be on aggressive treatment for their lung disease.” ....

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Online mental health intervention improves anxiety in isolated scleroderma patients during the pandemic


Online mental health intervention improves anxiety in isolated scleroderma patients during the pandemic
People with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and depression improve after receiving online mental health intervention through an international study involving investigators from Michigan Medicine.
The paper, published in the
Lancet Rheumatology, analyzed the mental health progress of over 150 people with scleroderma, a disease that causes tightening of the skin and connective tissues. Researchers randomized patients to either receive video support intervention or be put on a waitlist, finding mental health outcomes improved after the program finished. ....

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