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The TENSION trial, which was stopped early for efficacy, selected patients using widely available non-contrast CT or CT angiography and should lead to more patients being considered for treatment.
An otherwise negative trial may have identified a subgroup of patients likely to respond well to this potential transcatheter therapy for heart failure.
Were the GLP-1 receptor agonist drug's apparent benefits in STEP-HFpEF due solely to weight loss or additional mechanisms? The trial offers a clue, experts say.
Four experts explain nuances of the multidrug strategy and why it should be easy to implement. Given its slow uptake in practice, what forces are conspiring against it?
Tapering is best reserved for those in complete remission with stable disease for at least 6 months, although many individual patient characteristics must be taken into account, experts say.