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Endocarditis can present with many different clinical scenarios, so making the diagnosis can be challenging, says a co-chair of newly issued European guidelines for managing this disease.
In the randomized trial QUEST trial, a traditional Chinese medicine called qiliqiangxin provided significant reductions in CV death and hospitalization on top of guideline-directed therapy in HFrEF.
The trial "should make complete revascularization the standard of care in MI," and advanced age alone "should no longer be considered a contraindication," said an expert.
The largest ever study of IV iron supplementation in patients with heart failure failed to meet a new rigorous definition of significance, and the results were generally regarded as disappointing.
In STEP-HFpEF, a prospective, randomized study of adults with HFpEF and obesity, weekly semaglutide weight-loss injections for 1 year led to substantial improvements in physical function and symptoms.