Valisa Hedrick and colleagues argue that current evidence on non-sugar sweetener intake is inadequate, and further research is needed to determine the health effects of individual non-sugar sweeteners, especially in specific population subgroups ### Key messages Non-sugar sweeteners are commonly used as replacements for added sugars, both in the general population and among people with obesity and diabetes. Because of ongoing efforts to lower added sugar intake, non-sugar sweeteners have become ubiquitous in the global food supply. The global market for non-sugar sweeteners is expected to gro...