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No benefit of vitamin K in improving mortality or reducing calcification in dialysis patients: Study

Romania: A systematic review and meta-analysis published in the Clinical Kidney Journal summarized the impact of vitamin K supplementation in dialysis patients.The researchers found that vitamin K is. ....

Adrian Covic , Spitalul Clinic Drci Parhon , Kidney Journal , Clinical Kidney Journal , Vitamin K , Chronic Kidney Disease , Vascular Calcification , Vitamin K1 , Kd Mbd ,

"Calcium isotopes as a biomarker for vascular calcification in chronic " by Anthony Dosseto, Kelly Lambert et al.

Calcium balance is abnormal in adults with chronic kidney disease (CKD) and is associated with the development of vascular calcification. It is currently not routine to screen for vascular calcification in CKD patients. In this cross-sectional study, we investigate whether the ratio of naturally occurring calcium (Ca) isotopes, 44Ca and 42Ca, in serum could be used as a noninvasive marker of vascular calcification in CKD. We recruited 78 participants from a tertiary hospital renal center: 28 controls, 9 subjects with mild-moderate CKD, 22 undertaking dialysis and 19 who received a kidney transplant. For each participant, systolic blood pressure, ankle brachial index, pulse wave velocity, and estimated glomerular filtration rate were measured, along with serum markers. Calcium concentrations and isotope ratios were measured in urine and serum. While we found no significant association between urine Ca isotope composition (noted δ44/42Ca) between the different groups, δ44/42Ca values i ....

Chronic Kidney Disease , Mineral Balance , Vascular Calcification ,

Frontiers | Non-alcoholic Fatty Liver Disease Is Associated With Aortic Calcification: A Cohort Study With Propensity Score Matching

Abstract Objectives: Non-alcoholic fatty liver disease (NAFLD) greatly affects cardiovascular disease, but evidence on the associations between NAFLD and markers of aortic calcification is limited. We aim to evaluate the association between NAFLD and aortic calcification in a cohort of Chinese adults using propensity score-matching (PSM) analysis. Methods: This prospective cohort study involved adults who underwent health-screening examinations from 2009 to 2016. NAFLD was diagnosed by abdominal ultrasonography at baseline, and aortic calcification was identified using a VCT LightSpeed 64 scanner. Analyses included Cox proportional-hazards regression analysis and PSM with predefined covariates (age, gender, marital and smoking status, and use of lipid-lowering drugs) to achieve a 1:1 balanced cohort. Results: Of 6,047 eligible participants, 2,729 (45.13%) were diagnosed with NAFLD at baseline, with a median age of 49.0 years [interquartile range: 44.0–55.0]. We selected 2,339 pairs o ....

United States , Xiao Tang Shan , Nei Mongol , Mario Masarone , Vasc Pharmacol , Henryl Wymer , J Vasc Endovasc , Al Rifai , Gastroenterol Hepatol , Arterioscler Thromb Vasc , Van Poucke , Association Of Nonalcoholic Fatty Liver Disease , Natural Public Welfare Fund Of Zhejiang Province , Jinan University , Shenzhen Nanshan Centre For Chronic Disease , American College Of Gastroenterology , Key Laboratory Of Diagnosis , Artery Risk Development In Young Adults , Key Projects Of Ningbo Public Welfare Fund , American Gastroenterological Association , Technology Foundation Of Zhejiang Province , Association Between Liver Fat , Samsung Medical Center Health Promotion , National Age , Risk Factors For Development Of Intimal Hyperplasia , Health Science ,