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Diabetic ketoacidosis is a life-threatening metabolic crisis that can occur at presentation of type 1 diabetes, with acute (potentially fatal) complications including cerebral oedema and arrhythmias, and longer-term evidence of worsening glycaemic control1 and neurocognitive deficits in those presenting with diabetic ketoacidosis2 compared to those presenting without.
On Aug 26, 2022, Pfizer and BioNTech announced that they had applied to the European Medicines Agency to have their omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine authorised as a booster dose. The companies submitted an equivalent application to the US Food and Drug Administration (FDA) on Aug 22. The vaccine combines mRNA coding for the spike protein of the Wuhan strain of SARS-CoV-2, which is the basis of the original Pfizer-BioNTech vaccine, with mRNA coding for the spike protein of the omicron BA.4 and BA.5 subvariants.
As of May, 2022, the SARS-CoV-2 virus has caused 521 million COVID-19 cases and at least 6 million deaths, worldwide.1 Although the COVID-19 pandemic has led to breathtaking vaccine developments, early treatments to prevent progression of COVID-19, especially in those who are most vulnerable, are urgently needed. But to deploy such treatment will take a substantial change in the perception and management of upper respiratory infections, including COVID-19.
The Cuban Abdala protein subunit vaccine was highly effective in preventing severe illness and death from COVID-19 under real-life conditions.
Health diplomat who helped guide UK health and development funding strategy. Born on March 10, 1973 in Woking, UK, he died on May 29, 2022 in Geneva, Switzerland, aged 52 years.