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A genetic form of frontotemporal dementia is associated with abnormal lipid accumulation in the brain fueled by disrupted cell metabolism. The findings could pave the way for new targeted therapies for FTD.
Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide.
A new study sheds light on the basic biology of frontotemporal dementia caused by a particular genetic mutation.
Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide. Yet despite its prevalence, there are few effective treatments, in part because scientists still don’t understand how exactly dementia arises on a cellular and molecular level.