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Residue analysis suggests ritual use of tobacco at the ancient Mesoamerican city of Cotzumalhuapa, Guatemala
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NQAC Dublin colleagues explain why the company developed an in-house method for the quantitative determination of five Alternaria toxins.
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androgen receptor gene (AR), a variable number of CAG repeats. Moreover, there is preliminary evidence that the relationship between testosterone, CAG repeat length, and the severity of depressive symptoms may differ between subclinical and overt depression, but this has neither been studied in a clinical sample of adolescents with depression nor compared...
LC / MS performance: It makes sense for a mass spec user to minimise the void volume between the column and the MS Source. This dead volume can be the cause of the chromatography peak tailing. See the Spectrogram below: The spectrogram B is a standard configuration, void volume of 50μL Analysis of two couples of isobaric (250 and 264 m/z) substrate and metabolites performed on the Agilent 1290 Infinity UHPLC / Agilent 6460). Mobile phase: ammoniumformate 20mM pH 9 buffer and acetonitrile. Elution mode: 15%-35% of organic modifier in 3 min at 600_L/min. Injection volume: 2μL. Using the same ...