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While Derrick Henry is always a threat when these two teams face off, offensive line play takes center stage in this AFC South matchup.
The Indianapolis Colts have everything to gain as the rival Tennessee Titans come to town on Sunday. After their first win, the Colts very much need a division win.
What to watch for in every game. Bold predictions. Fantasy advice. Key stats to know. And, of course, final score picks. It's all here for Week 4.
The Indianapolis Colts will list linebacker Shaquille Leonard and defensive tackle DeForest Buckner as questionable while safety Julian Blackmon has been ruled out ahead of their matchup with the Tennessee Titans on Sunday.
The Los Angeles Chargers will face the Houston Texans in Week 4 as they look to get back in the win column.