How the body encourages obesity, and what can be done to reverse the process
Researchers at UC San Diego identified a molecule that protects stored fat in obese mice. But they also found a way to make it turn off.
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Researchers at UC San Diego identified a molecule that protects stored fat in obese mice. But they also found a way to make it turn off.
UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading
The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.
<p>UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.</p>