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Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a study published in the journal Nature Plants, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.

“Great Discoveries in Medicine: From Ayurveda to X-rays, Cancer to Covid” and edited by William and Helen Bynum; Thames & Hudson (352 pages, $16.95 paper) ——— Medicine isn’t magic. It

Divided into broad sections — “Discovering the Body” and “Tools of the Trade” ― the book explains how, over thousands of years, people have studied how our bodies work and invented an array of chemicals and machines to make them work better.

Anabolic steroids, also known as anabolic-androgenic steroids, drugs that mimics testosterone hormone in males. testosterone in its capacity to boost the development of muscle tissue, as well as its advancement of male secondary sexual characteristics. Anabolic steroids are utilized medically for humans to treat many ailments, such as anemia, hypogonadism and breast cancer

Award-winning clinical endocrinologist Professor Wiebke Arlt will be the new Director of the Medical Research Council London Institute of Medical Scienc...