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Myelination in the brain may be key to 'learning' opioid addiction

Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids. ....

United Kingdom , Belgin Yalcin , Michelle Monje , Robertj Kleberg Jr , National Cancer Institute , National Institute Of Neurological Disorders , Dean Postdoctoral Fellowship At Stanford University , Cancer Research United Kingdom , National Institute For Drug Abuse , Helenc Kleberg Foundation , Wu Tsai Neurosciences Institute Neurochoice Initiative , Gatsby Charitable Foundation , Milan Gambhir Professor , Pediatric Neuro Oncology , National Institute , Neurological Disorders , Pioneer Award , Drug Abuse , Cancer Grand Challenges , Child Health Research Institute , Stanford University Postdoctoral Award , Postdoctoral Fellowship ,

How opioid withdrawal threatens social support

New research in mice indicates how opioid withdrawal causes social aversion. In humans, that can endanger recovery. ....

Matthew Pomrenze , Brian Knutsen , Keith Humphreys , Robert Malenka , Wu Tsai Neurosciences Institute Neurochoice Initiative , Neurochoice Initiative , Wu Tsai Neurosciences Institute , Stanford University , Narcotics Anonymous ,

Social aversion during opioid withdrawal reflects blocked serotonin cues, mouse study finds

Neuroscientist Robert Malenka and his team have identified a molecular link between opioid withdrawal and social aversion in the brains of mice suggesting the potential to help people in recovery from opioid addiction reconnect with their social support networks ....

Matthew Pomrenze , Brian Knutsen , Keith Humphreys , Robert Malenka , Wu Tsai Neurosciences Institute Neurochoice Initiative , Neurochoice Initiative , Malenka Lab , Wu Tsai Neurosciences Institute , Wu Tsai Neurosciences Institute Image , Nancy Pritzker Professor , Fontejon Photography , Narcotics Anonymous ,

Brain imaging links stimulant-use relapse to distinct nerve pathway

A new study by scientists with the Wu Tsai Neurosciences Institute’s NeuroChoice Initiative reveals that relapse may be linked to quite different brain circuits than addiction itself. ....

United States , Kellyh Macniven , Josiah Leong , Nicholas Weiler , Brian Knutson , Loreen Tisdall , Kelly Macniven , Wu Tsai Neurosciences Institute Neurochoice Initiative , Neurochoice Initiative ,