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JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies. ....

France General , Lily Ramsey , Jerome Hadjadj , American College Of Rheumatology , American College , Lassistance Publique , Blood Vessels , Bone Marrow , Sex Chromosome , X Linked ,

What is Borjeson-Forssman-Lehman Syndrome?

Borjeson-Forssman-Lehman syndrome or BFLS is an X-linked genetic disorder encompassing a wide range of symptoms. ....

Nucleosome Remodeling , Borjeson Forssman Lehman Syndrome , X Linked ,

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys. ....

Parva Thakkar , Megan Craig , Faculty Department Of Biochemistry , Subash Sad , Ottawa Faculty , Rare Disease , Epstein Barr Virus , Immune System , X Linked ,