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Tweak could lead to COVID vax that fights new variants

The new design "could be used not just for SARS-CoV-2 and other related viruses, but also for other clinically important pathogenic viruses." ....

Yashavantha Vishweshwaraiah , Nikolay Dokholyan , Centers For Disease , University Of North Carolina At Charlotte , National Institutes Of Health , Penn State College Of Medicine , Passan Foundation , Huck Institutes Of The Life Sciences , Penn State College , Disease Control , Advanced Functional , Penn State , North Carolina , Huck Institutes , Life Sciences , National Institutes ,

New engineered proteins could be used to develop adaptation-proof COVID vaccine

A vaccine design approach that could protect against new variants of SARS-CoV-2 the virus that causes COVID-19 but also potentially protects against other coronaviruses is one step closer to reality as a result of research at Penn State College of Medicine. The scientists used areas of the SARS-CoV-2 virus that are less susceptible to mutation to engineer proteins called immunogens, which can elicit an immune response. ....

Suresh Kuchipudi , Abhinay Gontu , Brendan Rackley , Morgan Chandler , Kirill Afonin , G Thomas Passananti , Yashavantha Vishweshwaraiah , Neil Christensen , Brianna Hnath , Jian Wang , Nikolay Dokholyan , Centers For Disease , University Of North Carolina At Charlotte , National Institutes Of Health , Penn State College Of Medicine , Passan Foundation , Department Of Pharmacology , Huck Institutes Of The Life Sciences , Penn State College , Passananti Professor , Disease Control , Advanced Functional Materials , Neela Yennawar , Penn State Huck Institutes , Life Sciences , North Carolina ,

Penn State researchers engineer protein that could be used to develop one covid vaccine

Despite receiving one of the three covid-19 vaccines available in the U.S., many Americans continue to become infected with the virus. Penn State researchers hope recently engineered proteins could put an end to that cycle. The proteins, called immunogens, could protect people from new covid-19 variants — and other coronaviruses, ....

United States , Amesh Adalja , Yashavantha Vishweshwaraiah , Nikolay Dokholyan , University Of North Carolina , Penn State Engineered , Huck Institutes , North Carolina , Penn State ,

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

A vaccine design approach that could protect against new variants of SARS-CoV-2, the virus that causes COVID-19, but also potentially protects against other coronaviruses is one step closer to reality as a result of Penn State College of Medicine research. ....

G Thomas Passananti , Yashavantha Vishweshwaraiah , Nikolay Dokholyan , Emily Henderson , Centers For Disease , Penn State College Of Medicine , Department Of Pharmacology , Penn State College , Passananti Professor , Vice Chair , Disease Control , Genomics Industry Focus , Advanced Functional Materials , Covid 19 , Ngiotensin Converting Enzyme 2 , Immune Response , Ars Cov 2 , Spike Protein ,

Newly engineered protein could be used to develop adaptation-proof COVID vaccine

A vaccine design approach that could protect against new variants of SARS-CoV-2 the virus that causes COVID-19 but also potentially protects against other coronaviruses is one step closer to reality as a result of research at Penn State College of Medicine. The scientists used areas of the SARS-CoV-2 virus that are less susceptible to mutation to engineer proteins called immunogens, which can elicit an immune response. ....

Suresh Kuchipudi , Abhinay Gontu , Brendan Rackley , Morgan Chandler , Kirill Afonin , G Thomas Passananti , Yashavantha Vishweshwaraiah , Neil Christensen , Brianna Hnath , Jian Wang , Nikolay Dokholyan , Centers For Disease , University Of North Carolina At Charlotte , National Institutes Of Health , Penn State College Of Medicine , Passan Foundation , Department Of Pharmacology , Huck Institutes Of The Life Sciences , Penn State College , Passananti Professor , Disease Control , Advanced Functional Materials , Neela Yennawar , Penn State Huck Institutes , Life Sciences , North Carolina ,