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Poor survival after heart attack linked to excess levels of signaling protein in heart


 E-Mail
(Philadelphia, PA) - About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.
Now, in new work, scientists at the Lewis Katz School of Medicine (LKSOM) at Temple University identify a path to a promising novel therapeutic strategy, taking aim at a molecule in the heart known as G protein-coupled receptor kinase 5 (GRK5). In a study published online in the journal
Cardiovascular Research, the scientists show in mice that reducing GRK5 levels can significantly improve survival following heart attack. ....

United States , Temple University , Haley Christine Murphy , Stevenr Houser , Rajika Roy , Jessica Ibetti , Douglasg Tilley , Michela Piedepalumbo , Giuseppe Rengo , Ericw Barr , Anna Maria Lucchese , Giulia Borghetti , Erhe Gao , Walterj Koch , Laurela Grisanti , American Heart Association , Division Of Geriatrics , National Institutes Of Health , Lewis Katz School Of Medicine , Department Of Pharmacology , Cardiovascular Research Center , Federico Ii University , Department Of Translational Medical Sciences , University Of Missouri , Cardiovascular Research , College Of Veterinary Medicine ,

Naples detects rare new covid-19 variant never seen in Italy


Naples detects rare new covid-19 variant never seen in Italy
17 Feb, 2021
First time the rare covid-19 variant has been detected in Italy.
A new, rare variant of the covid-19 virus has been detected in the southern Italian city of Naples, in the first known case in Italy of the B. 1. 525 strain.
News of the strain was announced by the regional Campania government last night after it was identified by the Federico II University and the Pascale research institute in Naples.
So far they have been around 100 cases of the strain found around the world, including in Denmark, Nigeria, the UK and the US, reports Italian news agency ANSA. ....

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