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Subcutaneous GP IIb/IIIa Inhibitor in STEMI Is Fast, Potent in Early Study


May 18, 2021
RUC-4 (CeleCor Therapeutics), an investigational glycoprotein IIb/IIIa inhibitor (GPI) administered by subcutaneous injection, provides rapid and powerful platelet inhibition in patients with STEMI, according to findings from Cel-02, a phase IIa study.
Average platelet inhibition 15 minutes after the injection increased across three doses, from 77.5% with the lowest dose to 87.5% with the middle dose and 91.7% with the highest dose (
P = 0.002 for trend), Jurriën ten Berg, MD, PhD (St. Antonius Hospital, Nieuwegein, the Netherlands), reported during the virtual EuroPCR 2021.
RUC-4 was well tolerated among the 27 patients in the trial, with one injection-site reaction and two major bleeds, both related to perforation as the guidewire passed through a side branch of the radial artery. ....

Region Flamande , Kai Zheng , Pascal Vranckx , Davide Capodanno , Phd University Of Catania , Idorsia Pharmaceuticals , Phd Heart Centre Hasselt , Celecor Therapeutics , Antonius Hospital , Willem Bor , Heart Centre Hasselt , கை ஜெங் , டேவிட் காபோடான்னா , ஃப்ட் பல்கலைக்கழகம் ஆஃப் கேடேநிய , அன்டோனியஸ் மருத்துவமனை ,

Update: trams naar IJsselstein rijden weer, ontspoorde tram weggesleept

Update: trams naar IJsselstein rijden weer, ontspoorde tram weggesleept
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Saturday April , Nieuwegein Able , Province Utrecht , Antonius Hospital , சனிக்கிழமை ஏப்ரல் , அன்டோனியஸ் மருத்துவமனை ,