STEMI Trial Fails to Support Post-PCI Anticoagulation
The randomized RIGHT trial, testing 48 hours of post-PCI anticoagulation in STEMI patients, failed to document either benefit or increased risk.
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The randomized RIGHT trial, testing 48 hours of post-PCI anticoagulation in STEMI patients, failed to document either benefit or increased risk.
NSTEMI patients with blockages are delayed getting to the cath lab and fare worse than their counterparts with STEMI.
Latest data from the MASTER DAPT trial show similar results in the subgroup of patients who underwent complex PCI as in the main trial.
Complex HBR patients had the most to gain from longer DAPT, but even here, the shorter regimen seemed to hold up.
May 18, 2021 RUC-4 (CeleCor Therapeutics), an investigational glycoprotein IIb/IIIa inhibitor (GPI) administered by subcutaneous injection, provides rapid and powerful platelet inhibition in patients with STEMI, according to findings from Cel-02, a phase IIa study. Average platelet inhibition 15 minutes after the injection increased across three doses, from 77.5% with the lowest dose to 87.5% with the middle dose and 91.7% with the highest dose ( P = 0.002 for trend), Jurriën ten Berg, MD, PhD (St. Antonius Hospital, Nieuwegein, the Netherlands), reported during the virtual EuroPCR 2021. RUC...