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WHO has received user feedback on an elevated risk for false SARS-CoV-2 results when testing specimens using RT-PCR reagents on open systems.As with any diagnostic procedure, the positive and negative predictive values for the product in a given testing population are important to note. As the positivity rate for SARS-CoV-2 decreases, the positive predictive value also decreases. This means that the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as positivity rate decreases, irrespective of the assay specificity. Therefore, healthcare providers are encouraged to take into consideration testing results along with clinical signs and symptoms, confirmed status of any contacts, etc. ....

Great Barrington , United Kingdom , United States , New York , University Hospital , Sunetra Gupta , Barbara Yaffe , Bobby Rajesh Malhotra , Dominic Raab , Anthony Fauci , Matthew Oughton , Gina Kolata , Rajesh Kumar Malhotra , Jay Bhattacharya , Carl Heneghan , Michael Levitt , Ngozi Ezike , Pieter Borger Msc , Elon Musk , Mike Yeadon , Roberth Shmerling , Martin Kulldorff , Bw Research , Toronto Public Health , Illinois Department Of Public Health , Senior Faculty Editor At Harvard Health Publishing ,