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Current vaccines and therapies may be less effective at neutralizing new SARS-CoV-2 variants


Current vaccines and therapies may be less effective at neutralizing new SARS-CoV-2 variants
A new study of the U.K. and South Africa variants of SARS-CoV-2 predicts that current vaccines and certain monoclonal antibodies may be less effective at neutralizing these variants and that the new variants raise the specter that reinfections could be more likely.
The study was published in
Nature on March 8, 2021. A preprint of the study was first posted to BioRxiv on January 26, 2021.
The study s predictions are now being borne out with the first reported results of the Novavax vaccine, says the study s lead author David Ho, MD. The company reported on Jan. 28 that the vaccine was nearly 90% effective in the company s U.K. trial, but only 49.4% effective in its South Africa trial, where most cases of COVID-19 are caused by the B.1.351 variant. ....

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CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients


CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients
A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.
Results of the trial, published recently in the
New England Journal of Medicine, were significantly better than those seen with other therapies available to heavily relapsed and refractory myeloma patients who had already received the three main classes of treatment. Nearly three-quarters of the patients had at least a partial response to the therapy. About a third achieved a complete remission, with the disappearance of all traces of cancer. ....

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Antibody-mediated Rejection Market to Exhibit a Healthy CAGR of 17.5% During the Forecast Period, Affirms DelveInsight


Antibody-mediated Rejection Market to Exhibit a Healthy CAGR of 17.5% During the Forecast Period, Affirms DelveInsight
LAS VEGAS, March 9, 2021 /PRNewswire/ DelveInsight s
Antibody-mediated Rejection (AMR) Market report provides a thorough comprehension of the Antibody-mediated Rejection, historical and forecasted epidemiology, and the AMR market trends in the 7MM [the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan]. The Antibody-mediated Rejection market report also proffers an analysis of recent Antibody-mediated Rejection treatment algorithm/practice, market drivers, market barriers, and unmet medical needs.
Some of the vital points of the
Antibody-mediated Rejection Market Research Report
DelveInsight s analysts estimate that the Antibody-mediated Rejection market is expected to exhibit promising growth fueled by an increased prevalence and the expected launch of novel therapies, such as ....

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