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SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026


SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026
The Southwest National Primate Research Center (SNPRC) at Texas Biomedical Research Institute (Texas Biomed) has been awarded more than $37 million from the National Institutes of Health (NIH) to continue operations into 2026. The P51 grant, given by the NIH Office of Research Infrastructure Programs, provides essential funding to house and care for nearly 2,500 non-human primates that are part of life-science research programs at Texas Biomed and partners around the globe.
Non-human primates play an essential role in pre-clinical research, including most recently helping to show that the Pfizer-BioNTech COVID-19 vaccine would be safe and effective for humans, accelerating the clinical trials. The support from NIH for our Center will ensure that we can continue this critical work in finding new treatments and vaccines against a variety of infectious diseases, while maintaining the absolute ....

Deepak Kaushal , Larry Schlesinger , Emily Henderson , National Primate Research Center , Health Outcomes , National Primate Research Centers , National Institutes Of Health , Office Of Research Infrastructure Programs , Texas Biomedical Research Institute Biomed , Southwest National Primate Research Center , Texas Biomedical Research Institute , Texas Biomed , National Institutes , Research Infrastructure Programs , Infectious Diseases Immunology , Comparative Medicine , தீபக் கௌஷள் , லாரி ஶ்லெஸிந்‌ஜர் , எமிலி ஹென்டர்சன் , தேசிய ப்ரைமேட் ஆராய்ச்சி மையம் , ஆரோக்கியம் ஔட்கம்ஸ் , தேசிய ப்ரைமேட் ஆராய்ச்சி மையங்கள் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , அலுவலகம் ஆஃப் ஆராய்ச்சி உள்கட்டமைப்பு ப்ரோக்ர்யாம்ஸ் , டெக்சாஸ் உயிர் மருத்துவ ஆராய்ச்சி நிறுவனம் பயோமெட் , தென்மேற்கு தேசிய ப்ரைமேட் ஆராய்ச்சி மையம் ,

Hybrid approach reveals details about genes involved in Meier-Gorlin syndrome


Hybrid approach reveals details about genes involved in Meier-Gorlin syndrome
Meier-Gorlin syndrome, or MGS, is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities. In severe cases, MGS results in miscarriages and stillbirths.
Igor Chesnokov, Ph.D., and his University of Alabama at Birmingham colleagues study this recessive, autosomal disorder in an unusual way by placing mutant human genes into fruit flies. Specifically, they look at one of the genes involved in MGS called Orc6.
In a study published in
Genetics, featured as a highlighted article, they used this animal model to probe the function of one human Orc6 mutation a Lysine 23 to Glutamic acid (K23E) substitution that was first reported in 2017. In people with MGS, the K23E mutation causes a similar observable developmental disorder as an Orc6 mutation that the Chesnokov team previously studied, Tyrosine 225 to Serine ....

United States , Maxim Balasov , Katarina Akhmetova , Igor Chesnokov , Emily Henderson , Department Of Biochemistry , National Institute , University Of Alabama At Birmingham , Origin Recognition Complex , American Journal , Medical Genetics , Molecular Genetics , Meier Gorlin Syndrome , General Medical Sciences , National Institutes , Research Infrastructure Programs , Precision Animal Modeling , Drosophila Core , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , துறை ஆஃப் உயிர் வேதியியல் , தேசிய நிறுவனம் , பல்கலைக்கழகம் ஆஃப் அலபாமா இல் பர்மிங்காம் , ஆரிஜிந் அங்கீகாரம் சிக்கலான , அமெரிக்கன் இதழ் , மருத்துவ ஜெநெடிக்ஸ் ,