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Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis - Full Text View


Nasal Polyp Score [ Time Frame: Baseline to Week 52 ]
Change from baseline in total Nasal Polyp Score at Week 52. The Nasal Polyp Score is the sum of the right and left nostril scores (maximum 8), as evaluated by nasal endoscopy.
Participant Reported Nasal Congestion [ Time Frame: Baseline to Week 52 ]
Change from baseline in Nasal Congestion score evaluated as part of the Nasal Polyposis Symptom Diary at Week 52. Nasal Congestion Score is captured by asking participants to rate the severity of their worst nasal congestion over the past 24 hours (0-None; 1-Mild; 2-Moderate; 3-Severe).
Secondary Outcome Measures
Nasal Polyp Score [ Time Frame: Baseline to Week 24 ] ....

Lund Mackay , University Of Pennsylvania Smell Identification Test , Primary Outcome Measures , Nasal Polyp Score , Nasal Congestion , Nasal Polyposis Symptom Diary , Congestion Score , Outcome Measures , Life Compared , Sinonasal Outcome Test , Nasal Outcome Test , Polyposis Surgery , Receiving Systemic Corticosteroids , Nasal Polyposis , Partial Opacification , Total Opacification , Near Complete Resolution , Nasal Polyps , Bronchodilator Forced Expiratory Volume , Comorbid Asthma , Aspirin Exacerbated Respiratory Disease , Nasal Congestion Score , Pennsylvania Smell Identification Test , Modified Lund Mackay , Nasal Peak Inspiratory Flow , Asthma Control ,

American Lung Association to Reduce Asthma-related ER and Hospital Visits for Communities Most Burdened by Asthma


Press release content from PR Newswire. The AP news staff was not involved in its creation.
American Lung Association to Reduce Asthma-related ER and Hospital Visits for Communities Most Burdened by Asthma
April 8, 2021 GMT
American Lung Association logo (PRNewsfoto/American Lung Association)
CHICAGO, April 8, 2021 /PRNewswire/ In the U.S., 24.8 million people are living with asthma, including 5.5 million children. Without proper management of the disease, asthma symptoms can worsen and result in asthma attacks, emergency department and hospital visits. While asthma affects all people, the burden is not shared equally, with children and low-income individuals most likely to have asthma and suffer from severe asthma attacks, hospitalization and even death. Asthma morbidity and mortality also disproportionately affects Black and Hispanic individuals. In an effort to improve health and prevent asthma-related emergency department and hospital visits, especially for t ....

United States , Allison Macmunn , Harold Wimmer , Centers For Disease , National Asthma Control Program , Lung Association , American Lung Association Promoting Asthma Friendly Environments , Charity Navigator , American Lung Association , Disease Control , Promoting Asthma Friendly Environments , Asthma Control , Childhood Asthma , Reducing Emergencies , American Lung Association President , Gold Level Guidestar Member , ஒன்றுபட்டது மாநிலங்களில் , ஹரோல்ட் வீம்மேர் , மையங்கள் க்கு நோய் , தேசிய ஆஸ்துமா கட்டுப்பாடு ப்ரோக்ர்யாம் , நுரையீரல் சங்கம் , தொண்டு நேவிகேட்டர் , அமெரிக்கன் நுரையீரல் சங்கம் , நோய் கட்டுப்பாடு , ஆஸ்துமா கட்டுப்பாடு , குழந்தை பருவம் ஆஸ்துமா ,

New Medication Reduces Asthma Exacerbations and Improves Lung Function in Patients with Severe, Uncontrolled Asthma


New Medication Reduces Asthma Exacerbations and Improves Lung Function in Patients with Severe, Uncontrolled Asthma
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Results from the phase 3 NAVIGATOR study was presented during the 2021 AAAAI Virtual Annual Meeting.
Tezepelumab has the potential to transform treatment for a broad population of patients with severe asthma irrespective of their type of inflammation, including those with and without an eosinophilic phenotype.”
MILWAUKEE (PRWEB)
February 26, 2021
Tezepelumab, a human monoclonal antibody, was found to be effective for patients with severe uncontrolled asthma in a phase 3 trial funded by AstraZeneca and Amgen, Inc. Data from the abstract was presented during the 2021 American Academy of Allergy, Asthma & Immunology (AAAAI) Virtual Annual Meeting. ....

United States , United Kingdom , City Of , Jonathan Corren , Andrew Menzies Gow , Imperial College London , Amgen Inc , Lung Division , American Academy Of Allergy , Virtual Annual , Asthma Control , Asthma Quality , Asthma Symptom Diary , Royal Brompton Hospital , Respiratory Medicine , Imperial College , American Academy , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , ஜொனாதன் கார்ரேன் , ஆண்ட்ரூ மென்ஸீஸ் கௌ , ஏகாதிபத்தியம் கல்லூரி லண்டன் , மகேன் இன்க் , நுரையீரல் பிரிவு , அமெரிக்கன் கலைக்கழகம் ஆஃப் ஒவ்வாமை ,

Survey: Half of the people with uncontrolled asthma smoke cannabis


Survey: Half of the people with uncontrolled asthma smoke cannabis
As the number of states increase where medical and recreational cannabis use is legal, so does the importance that physicians discuss with patients the effects of cannabis on those with asthma. A new survey in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology, shows that of those who used cannabis, about half smoked it while a third vaped – both inhalation routes likely to affect one s lungs.
It surprised me that over half of the cannabis users in this study who have asthma were smoking it. And further, of those with uncontrolled asthma, half reported smoking cannabis. We also found that people with asthma are not routinely being asked or advised by their physician about cannabis and how they are consuming it. ....

William Silvers , Joanna Zeiger , Emily Henderson , American College Of Allergy , Allergy Asthma Network , American College , Asthma Network , Asthma Control , வில்லியம் வெள்ளிகள் , எமிலி ஹென்டர்சன் , அமெரிக்கன் கல்லூரி ஆஃப் ஒவ்வாமை , ஒவ்வாமை ஆஸ்துமா வலைப்பின்னல் , அமெரிக்கன் கல்லூரி , ஆஸ்துமா வலைப்பின்னல் , ஆஸ்துமா கட்டுப்பாடு ,