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One of the World's Most Venomous Animals Is a Snail


The Atlantic
They lure their prey with the promise of sex and then kill them cold.
Paulo Oliveira / Alamy
The aptly named cone snail wears a house that resembles a Ben & Jerry’s receptacle, filled not with ice cream but with a squishy mollusk that sports an extendable, trunklike proboscis. The snails are superficially docile creatures, and can be painfully shy; sometimes they go weeks in a lab without taking a single bite of food, cringing at the slightest change in temperature, lighting, or human supervision. “These are not racing snails,” says Eric Schmidt, a biochemist at the University of Utah. ....

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Modifying Alpha Cells into Beta Cells Helps Treat Diabetes


Modifying Alpha Cells into Beta Cells Helps Treat Diabetes
by Angela Mohan on 
March 2, 2021 at 12:29 PM
PNAS.
More than 34 million Americans have diabetes, a disease characterized by a loss of beta cells in the pancreas. Beta cells produce insulin, a hormone necessary for cells to absorb and use glucose, a type of sugar that circulates in the blood and serves as cellular fuel.
In Type 2 diabetes, the body s tissues develop insulin resistance, prompting beta cells to die from exhaustion from secreting excess insulin to allow cells to take in glucose.
In Type 1 diabetes, which affects about 10 percent of the diabetic population, beta cells die from an autoimmune attack. Both kinds of diabetes lead to severely elevated blood sugar levels that eventually cause a host of possible complications, including loss of limbs and eyesight, kidney damage, diabetic coma, and death. ....

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