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Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study


Nicotinamide adenine dinucleotide (NAD
+) is pivotal to physiological processes, not only as the coenzyme of cellular oxidation–reduction reactions but also for the activation of NAD
+-consuming enzymes, such as sirtuins, poly-ADP-ribose polymerases (PARPs), cADP-ribose synthases, NADase (CD38), and mono-ADP-ribose transferases (ARTs) [1]. NAD
+ participates in more than 50% of all physiological processes, including mitochondrial biogenesis, cardiovascular protection, neuroprotection, oxidative stress, DNA damage repair, stem cell rejuvenation, and inflammation [2]. Low NAD
+ levels are associated with age-associated physical disability and diseases, such as metabolic syndrome and cardiovascular disease [1,2,3]. The NAD
+ salvage pathway, which utilizes NAD
+ precursors, is the predominant mechanism for maintaining cellular NAD ....

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High-intensity exercise generates more aerosols, aids in Covid spread


High-intensity exercise generates more aerosols, aids in Covid spread
​ By
IANS
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High-intensity exercise generates more aerosols, aids in Covid spread. (Photo by Mamoun Wazwaz/Xinhua/IANS). Image Source: IANS News
New York, May 5 : High-intensity exercise produces more respiratory aerosols that can be harmful and aid in the transmission of Covid-19, and using a high-efficiency particulate air (HEPA) device can effectively filter out the aerosols, finds a study.
Aerosols are a common component of breath, and a typical mode of transmission for respiratory viruses like Covid-19 to spread to other people and surfaces.
The researchers from Mayo Clinic in the US set up a special aerosol laboratory in a plastic tent with controlled airflow. Two types of laser beam particle counters were used to measure aerosol concentration at the front, back and sides of a person riding an exercise bike. Eight exercise volunteers wore equipment to ....

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HEPA filter reduces airborne respiratory particles generated during exercise that can transmit viruses


Date Time
HEPA filter reduces airborne respiratory particles generated during exercise that can transmit viruses
A pair of Mayo Clinic studies shed light on something that is typically difficult to see with the eye: respiratory aerosols. Such aerosol particles of varying sizes are a common component of breath, and they are a typical mode of transmission for respiratory viruses like COVID-19 to spread to other people and surfaces.
Researchers who conduct exercise stress tests for heart patients at Mayo Clinic found that exercising at increasing levels of exertion increased the aerosol concentration in the surrounding room. Then also found that a high-efficiency particulate air (HEPA) device effectively filtered out the aerosols and decreased the time needed to clear the air between patients. ....

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