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If You Want Some Good Ideas Make For the Cafe, Not the Library

If You Want Some Good Ideas Make For the Cafe, Not the Library
goodmenproject.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from goodmenproject.com Daily Mail and Mail on Sunday newspapers.

Ravi Mehta , Destination Innovation , Good Men Project , Premium Member , Premium Members , ரவி மேத்தா , இலக்கு கண்டுபிடிப்பு , நல்ல ஆண்கள் ப்ராஜெக்ட் , ப்ரீமியம் உறுப்பினர் , ப்ரீமியம் உறுப்பினர்கள் ,

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE) QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports. ....

United States , Evangelos Kiskinis , Kasper Roet , Xuan Huang , Clifford Woolf , Kevin Eggan , Brian Wainger , Emily Henderson , Pfizer Centers For Therapeutic Innovation , Harvard Stem Cell Institute , Quralis Corporation , Target Discovery , Boston Children , Pfizer Centers , Therapeutic Innovation , Ton Channel , Amyotrophic Lateral Sclerosis , Cell Imaging , Motor Neurons , Neurodegenerative Diseases , ஒன்றுபட்டது மாநிலங்களில் , வைவாந் ஹுவாங் , கிளிஃபோர்ட் கம்பளி , கெவின் எ.கா. , எமிலி ஹென்டர்சன் , ஃபைசர் மையங்கள் க்கு சிகிச்சை கண்டுபிடிப்பு ,

How Two Undergraduate Scientists Uncovered One of the Pharmaceutical Industries Biggest Secrets

How Two Undergraduate Scientists Uncovered One of the Pharmaceutical Industries Biggest Secrets
forbes.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from forbes.com Daily Mail and Mail on Sunday newspapers.

Ann Palladino , Kristenm John , Christopherj Giuliano , Alexanderr Chait , Clara Tucker , Jasonm Sheltzer , Devona Lukow , Zacharyc Galluzzo , Erinl Sausville , Chris Giuliano , Connor Abramowicz , Luwei Liu , Ann Lin , Jason Sheltzer , Genetics At Stanford University , Cold Spring Harbor Laboratory , Biology At Massachusetts Institute Of Technology , Science Translational Medicine , Massachusetts Institute , New York Timesarticle , Monet Lou Yuan , Translational Medicine , Drug Target , Drug Discovery , Drug Development , Drug Failure ,

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study
Vijay R. Varma ,
Roles
Conceptualization,
Data curation,
Formal analysis,
Investigation,
Methodology,
Project administration,
Supervision,
Visualization,
Writing – original draft,
Writing – review & editing
¶‡ These authors share first authorship on this work.
Affiliation
Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America
¶‡ These authors share first authorship on this work.
Affiliation
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Yang An, ....

United Kingdom , Lilliana Posey , Carol Brayne , National Cancer Institute , National Institute On , University Of Cambridge , Clinical Practice Research Datalink , Alzheimer Disease Metabolomics Consortium , Hepatocyte Nuclear Factor , Groupa Member , Laboratory Of Behavioral Neuroscience , Grouph Member , Alzheimer Disease Neuroimaging Initiative , Alzheimer Disease Neuroimaging Network , Groupi Member , Consortium Molecular Mechanisms Of The Vascular Etiology , Medicines Partnership , Groupc Member , Nuclear Receptor , Scientific Advisory Committee , National Institute On Aging , Baltimore Longitudinal Study , Disease Neuroimaging Initiative , Religious Orders Study , Aging Project , Creative Commons ,

Changes in how cholesterol breaks down in the body may accelerate progression of dementia

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IMAGE: Investigators with the National Institute on Aging, part of the National Institutes of Health, are searching for drug candidates that may correct the brain s metabolic abnormalities, such as cholesterol breakdown.
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Credit: Dr. Vijay R. Varma
The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer s disease and vascular dementia. However, the underlying mechanisms mediating this relationship are poorly understood. A study published in the open-access journal
PLOS Medicine by Vijay Varma and colleagues at the National Institute on Aging, part of the National Institutes of Health, in Baltimore, Maryland, suggests that disturbances in the conversion of cholesterol to bile acids (called cholesterol catabolism) may play a role in the development of dementia. ....

National Institutes Of Health , United States , United Kingdom , Lilliana Posey , Madhav Thambisetty , Vijay Varma , National Cancer Institute , Alzheimer Disease Neuroimaging Initiative , Consortium Molecular Mechanisms Of The Vascular Etiology , National Institute On , Research Article , Medicines Partnership , Laboratory Of Behavioral Neuroscience , National Institute On Aging , National Institute , National Institutes , Baltimore Longitudinal Study , Disease Neuroimaging Initiative , Translational Neuroscience , Drug Repurposing , Effective Alzheimer , Accelerated Medicines Partnership , Target Discovery , Preclinical Validation Project , Molecular Mechanisms , Vascular Etiology ,