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Wet Age-Related Macular Degeneration Market to Flourish with a 4.5% CAGR and has a Promising Outlook with Emerging Therapies, Estimates DelveInsight


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LAS VEGAS, March 17, 2021 /PRNewswire/ DelveInsight s
Wet Age-Related Macular Degeneration (Wet AMD) Market report provides a thorough comprehension of the Wet Age-Related Macular Degeneration, historical and forecasted epidemiology, and the Wet AMD market trends in the 7MM [the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom) and Japan]. The Wet Age-Related Macular Degeneration market report also proffers an analysis of recent Wet AMD treatment algorithm/practice, market drivers, market barriers, and unmet medical needs. 
Some of the vital points of the
The introduction of Anti-vascular endothelial growth factor (VEGF) as a standard Wet AMD treatment has led to a significant improvement in patients prognosis, allowing recovery and maintenance of visual function in the vast majority of cases.  ....

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REGENXBIO Reports Fourth Quarter and Full-Year 2020 Financial Results and Operational Highlights


Pivotal Program for RGX-314 for the Treatment of Wet Age-related Macular Degeneration (wet AMD)
REGENXBIO announced in January 2021 that it completed an End of Phase 2 meeting with the U.S. Food and Drug Administration (FDA) to discuss the details of a pivotal program to support a Biologics License Application (BLA). REGENXBIO plans to conduct two randomized, well-controlled clinical trials to evaluate the efficacy and safety of RGX-314 in patients with wet AMD, enrolling approximately 700 patients total. REGENXBIO expects to submit a BLA based on these trials in 2024.
ATMOSPHERE™, the first of two planned pivotal trials, is active and enrolling patients. The trial will enroll approximately 300 patients across two RGX-314 dose arms versus ranibizumab. The primary endpoint of the trial is non-inferiority to ranibizumab based on change from baseline in Best Corrected Visual Acuity (BCVA) at one year. ....

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