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Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication


Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication
In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China. Without foreseeing the global disaster to come, they wondered aloud how they might contribute.
Nearly a year and a half later, those three scientists and their many collaborators across three national laboratories have published a comprehensive study in Biophysical Journal that - alongside other recent, complementary studies of coronavirus proteins and genetics - represents the first step toward developing treatments for that viral infection, now seared into the global consciousness as COVID-19. ....

United States , Oak Ridge , Greg Hura , Andrzej Joachimiak , Emily Henderson , Lawrence Berkeley National Laboratory Lab , Protein Data Bank , Berkeley Lab Advanced Light Source , Argonne National Laboratory , Structural Biology Department , Bioimaging Division , Berkeley Lab Molecular Biophysics , Biophysical Journal , Lawrence Berkeley National Laboratory , Berkeley Lab , Structural Biology , Molecular Biophysics , Integrated Bioimaging , Oak Ridge National Laboratory , Advanced Light Source , Advanced Photon Source , High Flux Isotope Reactor , Spallation Neutron Source , Science National Virtual Biotechnology Laboratory , Added Joachimiak , ஒன்றுபட்டது மாநிலங்களில் ,