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Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021 According to the Johns Hopkins University, the COVID-19 pandemic has caused over 159 million confirmed cases and more than 3.31 million deaths as of today. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been in circulation globally for well over a year now. The virus has been mutating throughout this time, though at a slower pace when compared to the influenza virus and the human immunodeficiency virus (HIV). One SARS-CoV-2 variant of concern called the B.1.1.7 was found to be more infectious and fatal than other strains. The emergence of this variant highlighted the uneven pace of mutation and selection of variants. New bioinformatics tools are the need of the hour to clarify this and confirm a dynamic evolution by tracking the mutation rates of the spike protein. It generally takes 1 – 6 months for current variants causing COVID-19 case peaks and deaths to sur ....