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Llama 'nanobodies' have the potential to outwit human cytomegalovirus


Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus
Scientists have developed a nanobody - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and destroy this potentially deadly virus.
Around four out of five people in the UK are thought to be infected with HCMV, and in developing countries this can be as high as 95%. For the majority of people, the virus remains dormant, hidden away inside white blood cells, where it can remain undisturbed and undetected for decades. If the virus reactivates in a healthy individual, it does not usually cause symptoms. However, for people who are immunocompromised - for example, transplant recipients who need to take immunosuppressant drugs to prevent organ rejection - HCMV reactivation can be devastating. ....

United Kingdom , Martine Smit , Emily Henderson , University Of Cambridge , Nature Communications , Department Of Medicine , Vrije Universiteit Amsterdam , Timo De Groof , Joint First Author , Vrije Universiteit , Brian Groves , Elizabeth Elder , ஒன்றுபட்டது கிஂக்டம் , மார்டின் ஸ்மீட் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , இயற்கை தகவல்தொடர்புகள் , துறை ஆஃப் மருந்து , ஈயந் தோப்புகள் , எலிசபெத் மூத்தவர் ,