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Failure: A common friend on the path to PhD success

Failure: A common friend on the path to PhD success
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Supersymmetry-inspired microlaser arrays pave way for powering chip-sized optical systems

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IMAGE: Ring microlasers are eyed as potential light sources for photonic applications, but they first must be made more powerful. Combining multiple microlasers into an array solves only half of the.
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Credit: University of Pennsylvania
The field of photonics aims to transform all manner of electronic devices by storing and transmitting information in the form of light, rather than electricity. Beyond light s raw speed, the way that information can be layered in its various physical properties makes devices like photonic computers and communication systems tantalizing prospects.
Before such devices can go from theory to reality, however, engineers must find ways of making their light sources lasers smaller, stronger and more stable. Robots and autonomous vehicles that use LiDAR for optical sensing and ranging, manufacturing and material processing techniques that use lasers, and many other applications are also continually pushing ....

Haoqi Zhao , James Joseph , Jieun Yim , Zhifeng Zhang , Ritesh Agarwal , Tianwei Wu , Nataliam Litchinitser , Lliang Feng , Bikashkali Midya , Xingdu Qiao , Zihe Gao , University Of Pennsylvania School Engineering , Indian Institute Of Science Education , National Science Foundation , Computer Engineering At Duke University , Engineering Center , Singh Center , Army Research Office , National Nanotechnology Coordinated Infrastructure Program , Us Army Research Office , Department Of Materials Science , Sloan Research Fellowship , University Of Pennsylvania Materials Research Science , Applied Science , Materials Science , Systems Engineering ,

Antibody binding-site conserved across COVID-19 virus variants

Deb Kelly, professor of biomedical engineering, and a team of biomedical engineers used a novel toolkit of approaches to uncover the first full structure of a SARS-CoV-2 protein, with findings that could inform advanced treatments and vaccines. Learn more about these research findings through this Penn State News story.
Penn State College of Engineering
“We discovered new features about the N protein structure that could have large implications in antibody testing and the long-term effects of all SARS-related pandemic viruses,” said Deb Kelly, professor of biomedical engineering (BME), Huck Chair in Molecular Biophysics and director of the Penn State Center for Structural Oncology, who led the research. “Since it appears that the N protein is conserved across the variants of SARS-CoV-2 and SARS-CoV-1, therapeutics designed to target the N protein could potentially help knock out the harsher or lasting symptoms some people experience.” ....

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Nanotechnology Now - Press Release: Antibody binding-site conserved across COVID-19 virus variants: The structural revelation could have implications as a therapeutic target in all SARS-CoV-2 variants

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Home > Press > Antibody binding-site conserved across COVID-19 virus variants: The structural revelation could have implications as a therapeutic target in all SARS-CoV-2 variants
A Penn State research team found that the N protein on SARS-CoV-2 is conserved across all SARS-related pandemic coronaviruses (top, from left: SARS-CoV-2, civet, SARS-CoV, MERS). The protein differs from other coronaviruses, such as those that cause the common cold (bottom, from left: OC43, HKU1, NL63 and 229E).
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Kelly Lab/Penn State
Abstract:
A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers. ....

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Antibody binding-site conserved across COVID-19 virus variants

Antibody binding-site conserved across COVID-19 virus variants
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South Africa , United States , United Kingdom , Williamy Luqiu , Mariah Schroen , Jared Wilson , Deb Kelly , Michael Casasanta , Williamj Dearnaley , Mariaj Solares , Penn State Center , Integrative Biosciences Graduate Program , Penn State Materials Research Institute , Computer Engineering At Duke University , Department Of Electrical , Protochips Inc , Huck Institutes Of The Life Sciences , Penn State , Huck Chair , Molecular Biophysics , Structural Oncology , Raybiotech Life , Direct Electron , Materials Research Institute , Genomics Graduate Program , Huck Institutes ,