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New findings on the support and barriers to combat TB in high-burden countries


New findings on the support and barriers to combat TB in high-burden countries
Nine out of ten cases of tuberculosis appear in 30 identified low and middle-income countries, each of which has a national tuberculosis programme. The managers of these programmes agree that it is important to screen for tuberculosis outside of health facilities. However, each screening programme must have its own well-considered, sustainable strategy and sufficient resources for it to be meaningful - which is not always the case today. This is one conclusion drawn by Olivia Biermann s forthcoming thesis.
At a global level, tuberculosis (TB) is still one of the deadliest infection diseases, affecting an estimated 10 million people every year, primarily people living in poverty in low and middle-income countries. Roughly 90 percent of cases occur in 30 identified countries, including India, Vietnam and South Africa. However, nearly a third of those infected - 2.9 million people - receive neither ....

Republic Of , South Africa , Karolinska Institutet , Olivia Biermann , Kerri Viney , Emily Henderson , World Health Organization , Liverpool School Of Tropical Medicine , Birat Nepal Medical , Doctoral Student , Global Public Health , Maxine Caws , Birat Nepal Medical Trust , Liverpool School , Public Health , குடியரசு ஆஃப் , ஒலிவியா பிர்மாண் , கெர்ரி திராட்சை , எமிலி ஹென்டர்சன் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , லிவர்பூல் பள்ளி ஆஃப் வெப்பமண்டல மருந்து , பிரட் நேபால் மருத்துவ , முனைவர் மாணவர் , உலகளாவிய பொது ஆரோக்கியம் , லிவர்பூல் பள்ளி ,

Designing effective multidrug-resistant-TB treatments based on DNA sequencing


Designing effective multidrug-resistant-TB treatments based on DNA sequencing
Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly. While other typical pathogens, such as pneumococcal and pseudomonads, can already be identified by their growth in the microbiological laboratory in the first 72 hours, several weeks usually pass before tuberculosis bacteria grow in the lab. Thus it often takes one to two months before the efficacy of individual medicines can be tested.
However, these efficacy tests are essential for the effective treatment of multidrug-resistant tuberculosis (MDR-TB), which is becoming increasingly common. In these cases, the pathogen has become resistant, i.e. insensitive, to the best tuberculosis drugs, rifampicin and isoniazid. This is due to changes in the genome, so-called mutations, which ....

Harald Hoffmans , Florian Maurer , Christoph Lange , Stefan Niemann , Matthias Merker , Hans Peter Grobbel , Emily Henderson , Research Center Borstel , Borstel Department Of Medicine , Research Center , Peter Grobbel , Professor Matthias Merker , Borstel Department , National Reference Laboratory , Tuberculosis Bacteria , Antibiotic Resistance , புளோரியன் ம Ure ரர் , கிறிஸ்டோஃப் லாங்கே , ஸ்டீபன் நிஎமான்ன் , எமிலி ஹென்டர்சன் , ஆராய்ச்சி மையம் போர்ஸ்டல் , ஆராய்ச்சி மையம் , தேசிய குறிப்பு ஆய்வகம் ,

Patralekhaa recalls battling tuberculosis at teenage as she pens a gratitude letter for her late father | Hindi Movie News


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Actor Patralekhaa who recently lost her father Ajit Paul, took to her social media handles to share a long letter to her late father which has been penned by her. Thanking him for saving her life when Patralekhaa was diagnosed with tuberculosis at the age of 19, the letter mentioned several things about their adorable daughter-father relationship.
Talking about paying the last tribute, she revealed that although she’s good at final goodbye, she doesn’t know how to do the same for her darling papa. While the demise of her father has brought her down to her knees, a grieving Patralekhaa wrote to him, “Please, pick me up. I need you. I always will.” ....

Rajit Paul , Actor Patralekhaa , City Lights , அஜித் பால் , நகரம் விளக்குகள் ,

Dynamics of sputum conversion during effective tuberculosis treatment: A systematic review and meta-analysis

Author summary Why was this study done? Though cited in many countries’ national guidance, the evidence that individuals with pulmonary tuberculosis (TB) are rendered non-infectious by 2 weeks of effective TB treatment is challenged. This systematic review was commissioned by the World Health Organization to provide evidence to inform TB infection prevention and control guidelines. We sought to synthesise the available data on the clearance of potentially infectious TB bacteria from the sputum of patients after starting effective treatment. What did the researchers do and find? We performed systematic searches of literature databases to identify relevant articles, using predetermined inclusion criteria. Extracted data were synthesised using narrative summaries and meta-analyses. A minority of patients had clearance of TB bacteria from sputum at 2 weeks of effective treatment, as assessed by either sputum smear or culture. As expected, the proportion having cleared TB bacter ....

United States , Mengyun Liu , Maria Krutikov , Fuad Mirzayev , Guideline Development Group , Global Health , Lshtm Tb Centre , World Health Organization , Global Tb Department Guideline Development Group , Department Of Global Tb Programme , South America , North America , Creative Commons Attribution License , World Health , Alice Gonz , Mycobacterium Tuberculosis , Drug Therapy , Randomized Controlled Trials , Database Searching , Respiratory Infections , Systematic Reviews , ஒன்றுபட்டது மாநிலங்களில் , வழிகாட்டல் வளர்ச்சி குழு , உலகளாவிய ஆரோக்கியம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , தெற்கு அமெரிக்கா ,