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Normoglycemic, Hyperglycemic Impact on Micro- & Macrovascular Disease


High glucose levels, even in the normoglycemic range, may potentiate microvascular complications.   
Hyperglycemia can lead to a multitude of health complications. In persons with diabetes, and even in those without, it has been observed to lead to ischemic heart disease. Also, in people with diabetes, a high glucose level is a definitive risk factor for microvascular disease. Although this is known, it is uncertain if hyperglycemia increases the risk of peripheral micro- and macrovascular diseases in the general population. Additionally, it is unknown whether the extent of this same risk varies between vascular compartments.   
 
Previous studies have found complications of microvascular dysfunction in people with prediabetes, such as retinopathy and neuropathy. However, these findings can be misleading due to the accompanying cardiometabolic risk factors such as obesity, hyperlipidemia, and hypertension.     ....

Copenhagen City Heart Study , Copenhagen General Population , Practice Pearls , கோபெந்ஹேகந் நகரம் இதயம் படிப்பு , கோபெந்ஹேகந் ஜநரல் பாப்யுலேஶந் , ப்ர்யாக்டீஸ் முத்துக்கள் ,

Leisure physical activity is linked with health benefits but work activity is not


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Sophia Antipolis, 9 April 2021: The first large study showing that leisure time physical activity and occupational physical activity have opposite, and independent, associations with cardiovascular disease risk and longevity is published today in
European Heart Journal, a journal of the European Society of Cardiology (ESC).1
We adjusted for multiple factors in our analysis, indicating that the relationships were not explained by lifestyle, health conditions or socioeconomic status, said study author Professor Andreas Holtermann of the National Research Centre for the Working Environment, Copenhagen, Denmark.
The World Health Organization (WHO) recommends physical activity during both recreation and work to improve health.2 Previous studies have suggested that occupational activity is related to an increased risk for heart disease and mortality but have been too small to fully explain whether this was due to the manual work or because employees had unhe ....

Andreas Holtermann , Sophia Antipolis , Danish Heart Foundation , Lundbeck Foundation , European Society Of Cardiology , Danish Lung Association , Velux Foundation , World Health Organization , National Research Centre For The Working Environment , European Heart Journal , European Society , Professor Andreas Holtermann , National Research Centre , Working Environment , Copenhagen General Population Study , Professor Holtermann , Capital Region , Copenhagen General Population , Physical Activity , டேனிஷ் இதயம் அடித்தளம் , ஐரோப்பிய சமூகம் ஆஃப் இருதயவியல் , டேனிஷ் நுரையீரல் சங்கம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , தேசிய ஆராய்ச்சி மையம் க்கு தி வேலை சூழல் , ஐரோப்பிய இதயம் இதழ் , ஐரோப்பிய சமூகம் ,