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Immuno-oncology startup KAHR to work with Philadelphia university on new drugs

Illustrative image of cancer cells (Design Cells; iStock by Getty Images)
KAHR, a maker of cancer immunotherapies, said it has entered into an exclusive licensing agreement with Thomas Jefferson University in Philadelphia to develop and commercialize a number of new cancer drug candidates.
Under the agreement, the university is granting KAHR the license to develop and commercialize new immuno-oncology drug candidates based on fusion proteins. These drugs are complex structures made by fusing the natural sequence of different proteins to make them bind two or three targets on cancer and immune cells. The new drug candidates entering development are called DSP502 (TIGITxPD1) and DSP216 (LILRB2xSIRPa). ....

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KAHR Announces Exclusive Licensing Agreement with Thomas Jefferson University for Novel Platform of Bi- and Tri-Specific Fusion Proteins for Cancer Immunotherapy

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JERUSALEM, April 1, 2021 /PRNewswire/ KAHR, a cancer immunotherapy company developing novel multifunctional immuno-recruitment proteins, announced today that it has entered into a licensing agreement with Thomas Jefferson University a national doctoral research university and its clinical enterprise, Jefferson Health, located in Philadelphia, PA. Under the agreement, Thomas Jefferson University is granting KAHR an exclusive license to develop and commercialize multiple new drug candidates including DSP502, a TIGITxPD1 fusion protein, and DSP216, a LILRB2xSIRPa fusion protein for immuno-oncology.
With this agreement we are adding a second fusion protein platform to our portfolio, enabling us to broaden our immuno-oncology target pipeline and positioning KAHR as a world leader in the fusion protein space, said Yaron Pereg, Ph.D., Chief Executive Officer of KAHR. Both DSP502 and DSP216 focus on promising checkpoint pathways ....

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Biden Picks Dr. Nunez-Smith to Lead Health Equity Task Force

Dr. Marcella Nunez-Smith Takes Aim at Racial Gaps in Health Care
Appointed head of the incoming administration’s task force on health equity, the Yale University scientist “is not sitting in her ivory tower.”
Dr. Marcella Nunez-Smith will run the Biden administration’s task force on health equity. “The Biden-Harris team has been really clear on saying that our response and recovery needs to be equitable,” she said.Credit.Yale University
Jan. 8, 2021
Growing up in the United States Virgin Islands, Dr. Marcella Nunez-Smith saw firsthand what can happen in a community with limited access to health care. Her father, Moleto “Bishop” Smith Sr., was only in his 40s when he suffered a debilitating stroke that left him partly paralyzed and with slurred speech. ....

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Main Line Neurologist Studies the Intersection of Faith and Science

A Main Line Neurologist Studies the Intersection of Faith and Science
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Photos by Tessa Marie Images
Dr. Andrew Newberg may be a pioneer in his field, but he also understands that, when it comes to spirituality and the brain, it’s OK to say, “I don’t know.”
As a child, Dr. Andrew Newberg peppered his father with some serious questions about the concept of reality. “But he was very good at throwing it back at me,” Newberg recalls.
So he would have to find the answers on his own. In the months between his graduation from Haverford College and heading to medical school at the University of Pennsylvania, Newberg often meditated as he walked. Then he’d simply sit and think. Some of what he experienced he can’t explain to this day. It led directly to his studies on the impact of religious and spiritual experiences on the brain. This unconventional field is known as neurotheology, and Newberg is one of its pioneers. ....

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Pandemic is turning us into couch potatoes

Pandemic is turning us into couch potatoes
‘Any motion is better than just sitting around’
By CNN staff | December 15, 2020 at 2:33 PM EST - Updated December 15 at 5:55 PM
(CNN) – One of the side effects of the pandemic for many is a sedentary lifestyle.
Combine social isolation, working from home and binge-watching TV, it all adds up to Americans sitting for hours longer each day when compared to their pre-pandemic lifestyles.
Because of that, people are reporting new aches and pains, which doctors are directly linking to our inactivity.
“Muscles weaken a lot with just a little bit of inactivity and when muscles are weak … joints don’t work so well,” according to Dr. Angela Smith, a professor of orthopedics at Sidney Kimmel Medical College. ....

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