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Partner Therapeutics Announces Partnership with SIRS Therapeutics and F4 Pharma to Explore Potential Uses for FX06 in Biodefense Applications


Partner Therapeutics Announces Partnership with SIRS Therapeutics and F4 Pharma to Explore Potential Uses for FX06 in Biodefense Applications
FX-06 is a synthetic peptide with a broad spectrum of potential applications associated with endothelial barrier integrity, blood vessel permeability and inflammation
Potential applications include COVID-19, pandemic, chemical, biological, radiological and nuclear threats
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LEXINGTON, Mass., March 3, 2021 /PRNewswire/  Partner Therapeutics, Inc. (PTx), a commercial biotech company, announces a licensing and collaboration agreement with Munich-based SIRS Theraputics and Vienna-based F4 Pharma to support the development of FX-06, a synthetic peptide that has a broad spectrum of potential indications.  The partnership will focus on exploring potential collaborations with the U.S. Government to develop FX-06 as a medical countermeasure against high priority threats ....

New Zealand General , New Zealand , John Mcmanus , Anne Burger , Debasish Roychowdhury , Partner Therapeutics Inc , Biomedical Advanced Research , Department Of Defense Joint Program Executive Office , Strategic National , Chemical Biological Radiological Nuclear , Development Authority , Partner Therapeutics , Partners Therapeutics , Chief Technology Officer , Chief Business Officer , Defense Joint Program Executive Office , Strategic National Stockpile , Wellington Partners , புதியது ஜீலாந்து ஜநரல் , புதியது ஜீலாந்து , ஜான் மக்ம்யாநஸ் , அன்னே பர்கர் , செயலிழப்பு ரொயிசொவிதுறி , கூட்டாளர் சிகிச்சை இன்க் , துறை ஆஃப் பாதுகாப்பு கூட்டு ப்ரோக்ர்யாம் நிர்வாகி அலுவலகம் , மூலோபாய தேசிய ,

SARPAC Clinical Trial of Leukine® (sargramostim, rhu GM-CSF) in Hospitalized COVID-19 Patients Meets Primary Endpoint of Significant Improvement in Lung Function


COVID-19) study of inhaled Leukine
® (sargramostim, yeast-derived recombinant human GM-CSF) in hospitalized COVID-19 patients (NCT04326920).
1,2 This prospective, randomized, open-label study was led by University Hospital Ghent and conducted at five hospitals in Belgium. The study enrolled 81 patients with PCR-confirmed COVID-19 who were suffering from acute hypoxic respiratory failure requiring supplemental oxygen. The full study and translational results are being prepared for publication.
Lung dysfunction resulting in hypoxemia has been a hallmark of severe cases of COVID-19.
3,4,5  SARPAC was launched based on GM-CSF s role in restoring alveolar macrophages that have anti-inflammatory properties and serve to remove pathogens and other debris while maintaining alveolar surfactant. ....

United States , Robert Paine , Luisa Morales Nebreda , Debasish Roychowdhury , Bart Lambrecht , Van Damme , Partner Therapeutics Inc , Flanders Institute Of Biotechnology , Tanner Pharma Group , University Of Utah , Drug Administration , Division Of Pulmonary Medicine , Association Between Hypoxemia , Research On Sargramostim , Patient Health , Inflammation Research , Strategic National , Patient Program , Nuclear Defense , University Hospital Ghent , Partner Therapeutics , Hypoxic Respiratory Failure , Acute Respiratory Distress Syndrome , Pulmonary Medicine , Scientific Director , Flanders Institute ,