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Gene therapy s cellular benefits remain decades after treatment
ANI |
Updated: Mar 17, 2021 23:28 IST
Washington [US], March 17 (ANI): During an international collaboration recently between Great Ormond Street Hospital, the UCL GOS Institute for Child Health, and Harvard Medical School, it was found that the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells have been cleared by the body.
The research team monitored five patients who were successfully cured of SCID-X1 using gene therapy at GOSH. For 3-18 years patients blood was regularly analysed to detect which cell types and biomarker chemicals were present in their blood. The results showed that even though the stem cells transplanted as part of gene therapy had been cleared by the patients, the all-important corrected immune cells, called T-cells, were still forming. ....

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