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New proteins 'out of nothing'


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IMAGE: Regions of the protein s flexibility: not very flexible (blue), moderately flexible (green/yellow) and highly flexible (red). However, both the central alpha helix and the N-terminus (start of the protein) display.
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Credit: Adam Damry
Proteins are the key component in all modern forms of life. Haemoglobin, for example, transports the oxygen in our blood; photosynthesis proteins in the leaves of plants convert sunlight into energy; and fungal enzymes help us to brew beer and bake bread. Researchers have long been examining the question of how proteins mutate or come into existence in the course of millennia. That completely new proteins - and, with them, new properties - can emerge practically out of nothing, was inconceivable for decades, in line with what the Greek philosopher Parmenides said: Nothing can emerge from nothing (ex nihilo nihil fit). Working with colleagues from the USA and Australia, researchers from the Universi ....

College Of The Holy Cross , United States , Australian Capital Territory , Geoff Findlay , Prajal Patel , Adam Damry , Colin Jackson , Erich Bornberg Bauer , Andreas Lange , Brennen Heames , Nature Communications , Australian National University , Institute Of Evolution , Holy Cross , Molecular Biology , கல்லூரி ஆஃப் தி பரிசுத்த குறுக்கு , ஒன்றுபட்டது மாநிலங்களில் , ஆஸ்திரேலிய மூலதனம் பிரதேசம் , ஜியோஃப் கண்டுபிடிப்பு , கொலின் ஜாக்சன் , ஆண்ட்ரியாஸ் லாங்கே , இயற்கை தகவல்தொடர்புகள் , ஆஸ்திரேலிய தேசிய பல்கலைக்கழகம் , நிறுவனம் ஆஃப் பரிணாமம் , பரிசுத்த குறுக்கு , உயிர் வேதியியல் ,

Flashpoint: After 1 year: Vaccines, immunity and the end in sight

Last fall brought a huge surge of COVID-19 cases across the U.S. These occurred simultaneously and with similar severity almost nationwide, with little regard to the extent or enforcement of ....

Why do women have more reactions to COVID vaccines?


Why do women have more reactions to COVID vaccines?
Study: Women report worse vaccine side effects than men
By Chasity Maxie | March 11, 2021 at 7:52 PM CST - Updated March 11 at 7:52 PM
BIRMINGHAM, Ala. (WBRC) - A recent study from the Centers for Disease Control shows women report more side effects from COVID-19 vaccines than men.
But why are more women having these reactions?
A top Alabama public health doctor said the data is very preliminary, but women could be having more severe reactions than men because of a difference in genetics and hormones.
The CDC said the difference in reactions to vaccines between men and women is not new. But when it comes to the COVID-19 vaccines, women are more likely to report side effects from the shots. ....

United States , Karen Landers , Centers For Disease , Disease Control , State Health Officer , Side Effects , Severe Reactions , Covid 19 Vaccines , Dr Karen Landers , Women Report More Reactions , ஒன்றுபட்டது மாநிலங்களில் , கரேன் லேண்டர்கள் , மையங்கள் க்கு நோய் , நோய் கட்டுப்பாடு , நிலை ஆரோக்கியம் அதிகாரி , பக்க விளைவுகள் , கடுமையானது ரியாக்ஶந்ஸ் , டாக்டர் கரேன் லேண்டர்கள் , பெண்கள் அறிக்கை மேலும் ரியாக்ஶந்ஸ் ,

Beyond genes and environment, random variations play important role in longevity


Credit: John Skalicky/USC
A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.
University Professor Caleb Finch introduced the Tripartite Phenotype of Aging as a new conceptual model that addresses why lifespan varies so much, even among human identical twins who share the same genes. Only about 10 to 35 percent of longevity can be traced to genes inherited from our parents, Finch mentioned.
Finch authored the paper introducing the model with one of his former graduate students, Amin Haghani, who received his PhD in the Biology of Aging from the USC Leonard Davis School in 2020 and is now a postdoctoral researcher at UCLA. In the article, they propose that the limited heritability of aging patterns and longevity in humans is an outcome of gene-environment interactions, together with stochastic, or chance, variations in the body s cells. These random changes can inclu ....

Williamf Kieschnick , Amin Haghani , Leonard Davis School , University Professor Caleb Finch , Professor Caleb Finch , Davis School , Christopher Paul Wild , Cell Biology , Medicine Health , Developmental Reproductive Biology , Environmental Health , லியோனார்ட் டேவிஸ் பள்ளி , பல்கலைக்கழகம் ப்ரொஃபெஸர் காலேப் பிஞ்ச் , ப்ரொஃபெஸர் காலேப் பிஞ்ச் , டேவிஸ் பள்ளி , கிறிஸ்டோபர் பால் காட்டு , செல் உயிரியல் , மருந்து ஆரோக்கியம் , வளர்ச்சி இனப்பெருக்கம் உயிரியல் , சுற்றுச்சூழல் ஆரோக்கியம் ,