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Oxford study sheds light on level of antibodies needed to protect against COVID-19 symptoms Researchers in the UK have reported on the relationship between humoral (antibody) responses and protection against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) following immunization with AstraZeneca’s ChAdOx1 vaccine. The SARS-CoV-2 virus is the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic that continues to pose a threat to global public health and has now caused more than 3.92 million deaths worldwide. The study analyzed data from a phase 2/3 vaccine efficacy trial conducted across 19 sites in the UK. The team from the University of Oxford, NIHR Oxford Biomedical Centre, AstraZeneca PLC, Public Health England in Salisbury and the Oxford COVID Vaccine Trial Group say the analysis aimed to facilitate the development and licensure of future vaccines in situations where large vaccine efficacy trials are not feasible. ....
If you trace the history of pandemics, their natural course tends to have three waves. During the first wave, the aged and those with weak immune systems (immune-compromised individuals) are the worst hit; in them, the virus learns to circumvent the human body’s immunity. The young and those with strong immune systems the immune-uncompromised subset of the population remain ....
Oxford-AstraZeneca vaccine effective against B.1.1.7 SARS-CoV-2 variant The coronavirus disease (COVID-19) pandemic continues to spread globally, with new variants emerging. One of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is the B.1.1.7 or U.K. variant. It is still unclear if the developed vaccines can protect against new emerging variants. Now, researchers at the COVID-19 Genomics United Kingdom Consortium, the AMPHEUS Project, and the Oxford COVID-19 Vaccine Trial Group released the results of their exploratory analysis of a randomized controlled trial of the ChAdOx1 nCoV-19 (AZD1222) vaccine against the SARS-CoV-2 variant of concern 202012/01 or the B.1.1.7 variant. Published in ....