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Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2
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New vaccine candidate could be a cost-effective option against emerging SARS-CoV-2 variants


New vaccine candidate could be a cost-effective option against emerging SARS-CoV-2 variants
A multidisciplinary team of researchers is the first to show combining yeast-expression technology and a novel adjuvant formulation to produce a COVID-19 vaccine candidate is effective against SARS-COV-2 and promises to be easy to produce at large scale and cost-effective, important aspects for vaccinating people worldwide, especially in low- to middle-income countries. Results from the study, which applied lessons learned from the hepatitis b vaccine platform technology, are published online today in
Science Immunology.
Researchers from the Yerkes National Primate Research Center (NPRC) at Emory University, Infectious Disease Research Institute (IDRI), 3M and Texas Children s Hospital s Center for Vaccine Development at Baylor College of Medicine paired Baylor s SARS-CoV-2 Receptor Binding Domain (RBD) recombinant protein formulation vaccine candidate with IDRI s aluminum-base ....

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Why a Former Anti-Vax Influencer Got Her COVID-19 Shot


Heather SImpson is vaccinated against COVID-19 at Baylor University Medical Center in Dallas.
Tara Haelle
Heather Simpson dressed up as measles for Halloween in 2019 because it was, as she told her growing following on social media, the “least scary thing I could think of.” The Dallas mom was then a full-fledged anti-vaccine influencer, drawing tens of thousands of likes and comments on her Facebook posts that denied the safety and necessity of childhood vaccinations.
But today most of the thousands who recirculated those posts have abandoned and shunned her. On a mid-April afternoon, Simpson battled traffic into downtown Dallas to reach Baylor University Medical Center for her first dose of the Pfizer-BioNTech vaccine against COVID-19. Clad in jeans and a black “Kiss Me I’m Vaccinated” T-shirt and a mask the upbeat thirty-year-old said she wouldn’t back out, despite her anxiety. ....

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