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Researchers make 'bombshell' discovery of an entirely new kind of biomolecule


Date Time
Researchers make ‘bombshell’ discovery of an entirely new kind of biomolecule
A newfound biomolecule, consisting of RNA modified by sugars, could be present in all forms of life and might contribute to autoimmune disease.
By Holly Alyssa MacCormick
Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.
The novel biomolecule, dubbed glycoRNA, is a small ribbon of ribonucleic acid (RNA) with sugar molecules, called glycans, dangling from it. Up until now, the only kinds of similarly sugar-decorated biomolecules known to science were fats (lipids) and proteins. These glycolipids and glycoproteins appear ubiquitously in and on animal, plant and microbial cells, contributing to a wide range of processes essential for life. ....

United States , Stacy Malaker , Benson George , Kayvon Pedram , Holly Alyssa Maccormick , Alex Johnson , Karim Majzoub , Jan Carette , Stanford Bio , Howard Chang , Ryan Flynn , Carolyn Bertozzi , Stanford School Of Humanities , National Cancer Institute , National Science Foundation , Department Of Stem Cell , Damon Runyon Cancer Research , Dk Ludwig Professor Of Cancer Research , Cancer Research Of The United States , Maternal Child Health Research Institute , National Institute , Stanford Wu Tsai Neurosciences Institute , Yale University , Stanford Chemistry Biology Interface Predoctoral Training Program , National Institutes Of Health , Medicine For Human Health ,

Study dives deeper into genetic differences between modern and archaic humans


Date Time
Study dives deeper into genetic differences between modern and archaic humans
Researchers examined 14,000 genetic differences between modern humans and our most recent ancestors at a new level of detail. They found that differences in gene activation – not just genetic code – could underlie evolution of the brain and vocal tract.
By Taylor Kubota
A genome by itself is like a recipe without a chef – full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives – the Neanderthals and the Denisovans – there remain many unknowns regarding how differences in our genomes actually lead to differences in physical traits. ....

Stanford University , United States , San Francisco , Hunter Fraser , David Gokhman , Dmitri Petrov , Stanford Bio , Nadav Ahituv , Carly Weiss , Lana Harshman , Fumitaka Inoue , Taylor Kubota , University Of California , Stanford Center , Stanford Woods Institute For The Environment , School Of Humanities , National Institute Of Mental Health , Stanford Cancer Institute , National Human Genome Research Institute , Maternal Child Health Research Institute , Uehara Memorial Foundation , Kevin Douglas Professor , Stanford Bio X , Child Health Research Institute , Stanford Cancer , Stanford Woods Institute ,