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IMAGE: Infection of human intestinal epithelial cells by Salmonella Typhimurium during spaceflight aboard NASA Space Shuttle mission STS-131. view more
Credit: Graphic by Shireen Dooling for the Biodesign Institute at Arizona State University
Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.
Now, in the first study of its kind, Cheryl Nickerson, lead author Jennifer Barrila and their colleagues describe the infection of human cells by the intestinal pathogen Salmonella Typhimurium during spaceflight. They show how the microgravity environment of spaceflight changes the molecular profile of human intestinal cells and how these expression patterns are further changed in response to infection. In another first, the researchers were also able to detect molecular changes in the bacterial pathogen while inside the infected
New design studio opens on Nu uanu
Roberta Oaks in front her new store at Nu uanu and Pauahi.
Credit Noe Tanigawa / Hawaii Public Radio
Did you know that Nu uanu Ave is the center of town? Our major streets, like Beretania and King, are numbered North and South relative to Nu uanu. This essential thoroughfare is also home to several art hubs, including its newest addition, designer Roberta Oaks store. Oaks spoke with Noe Tanigawa about opening a brick-and-mortar location during the pandemic, as well as the inspiration for her designs.
Roberta Oaks
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