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Coronavirus | Challenges in developing, testing vaccines against variants

Coronavirus | Challenges in developing, testing vaccines against variants
Updated:
Updated:
February 20, 2021 21:33 IST
It is highly unlikely that we will be repeating phase-3 studies for every new vaccine based on a variant strain, but we do need alternative regulatory pathways, says Gagandeep Kang.
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It is highly unlikely that we will be repeating phase-3 studies for every new vaccine based on a variant strain, but we do need alternative regulatory pathways, says Gagandeep Kang.
With the emergence of three variants B.1.1.7 first found in Britain, B.1.1.248 first seen in Brazil, and B.1.351 first detected in South Africa less than two months after the first COVID-19 vaccine was approved for emergency use by the U.S. FDA, all companies have begun making booster shots or tweaking the existing vaccine based on the new variants. ....

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Switzerland REFUSES to approve AstraZeneca jab as 'new studies' needed

Switzerland REFUSES to approve AstraZeneca jab as new studies needed
Rachael Bunyan For Mailonline and Afp
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Switzerland has refused to approve the AstraZeneca Covid, vaccine with regulators raising concerns over insufficient test data and arguing new studies are needed.
It comes after France, Sweden and Germany advised against administering the jab to those over 65 and Emmanuel Macron claimed it was almost ineffective for the age bracket.
That is despite Oxford data published this week suggesting the jab is 76 per cent effective after just one dose, and may also prevent 67 per cent of infection.
British Prime Minister Boris Johnson has also weighed in, saying the jab is is very good and efficacious in all age groups. ....

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Denmark becomes latest country to recommend AstraZeneca jab for under-65s only

Denmark and Norway have become the latest European countries to recommend people aged over 65 should avoid the Oxford AstraZeneca vaccine.
Medical regulators in both countries said more evidence about the vaccine s effectiveness among older people is needed before it can be safely recommended to them.
Germany, France and Sweden have also discouraged people aged over 65 from taking the jab, while Switzerland has refused to approve it, saying new studies are needed.
It comes after a mighty row between the EU and AstraZeneca over the supply of jabs, and despite the fact that Oxford scientists who developed the vaccine and UK PM Boris Johnson have dismissed concerns about its safety. ....

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Switzerland REFUSES to approve AstraZeneca jab and says 'new studies' are needed

Switzerland has refused to approve the AstraZeneca Covid, vaccine with regulators raising concerns over insufficient test data and arguing new studies are needed.
It comes after France, Sweden and Germany advised against administering the jab to those over 65 and Emmanuel Macron claimed it was almost ineffective for the age bracket.
That is despite Oxford data published this week suggesting the jab is 76 per cent effective after just one dose, and may also prevent 67 per cent of infection.
British Prime Minister Boris Johnson has also weighed in, saying the jab is is very good and efficacious in all age groups.
Continental objections to the jab come amid a furious row between the EU and AstraZeneca over lagging supply, which has seen newly-unshackled Brexit Britain storm ahead in its immunisation roll-out. ....

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