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A link between childhood stress and early molars


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Early in her career neuroscientist Allyson Mackey began thinking about molars. As a researcher who studies brain development, she wanted to know whether when these teeth arrived might indicate early maturation in children.
I ve long been concerned that if kids grow up too fast, their brains will mature too fast and will lose plasticity at an earlier age. Then they ll go into school and have trouble learning at the same rate as their peers, says Mackey, an assistant professor in the Department of Psychology at Penn. Of course, not every kid who experiences stress or [is] low income will show this pattern of accelerated development. ....

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Kratom use rare, but more common among people with opioid use disorder


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Less than one percent of people in the United States use kratom, a plant-based substance commonly used to manage pain and opioid withdrawal, according to a study published in the
American Journal of Preventive Medicine. However, the use of kratom which is legal but carries the risk of addiction and harmful side effects is more prevalent among people who use other drugs, particularly those with opioid use disorder.
Derived from a tree native to Southeast Asia, kratom can be taken as a pill, capsule, or extract, or brewed as a tea. It acts on the brain s opioid receptors; at low doses, kratom is a stimulant, while at higher doses, it can relieve pain. Some people report using kratom as a substitute for opioids in an effort to limit their opioid use and ameliorate withdrawal. Others use kratom recreationally for relaxation or to self-treat pain, anxiety, or depression. ....

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Drug seizures plummeted early in the COVID-19 pandemic, then climbed once lockdowns lifted


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Law enforcement seizures of drugs, particularly marijuana and methamphetamine, dropped at the beginning of the COVID-19 pandemic, then increased significantly in the following months exceeding pre-pandemic seizure rates and providing clues about the impact of the crisis on substance use, according to a new study in the journal
Drug and Alcohol Dependence.
The research was conducted as part of the National Drug Early Warning System (NDEWS), which uses real-time surveillance to detect early signals of potential drug epidemics. NDEWS is led by a team of researchers at the University of Florida, New York University, and Florida Atlantic University, and is funded by the National Institute on Drug Abuse, part of the National Institutes of Health. ....

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