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Lilly Presents Patient-Reported Outcomes from the Positive Phase 3 monarchE Trial for Verzenio® at St. Gallen Virtual Congress 2021

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INDIANAPOLIS, March 17, 2021 /PRNewswire/ Eli Lilly and Company (NYSE: LLY) today announced patient-reported outcomes (PRO) for the investigational use of Verzenio
® (abemaciclib) in combination with standard adjuvant endocrine therapy (ET) for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) high risk early breast cancer (EBC). The PRO analysis included patients in both arms of the study and measured their experiences with side effects, symptoms, and health-related quality of life, in those receiving Verzenio plus ET versus ET alone. In one analysis, the PRO data indicated that most patients (approximately 70-75%) in both arms reported being bothered a little bit or not at all by treatment-related side effects. This analysis revealed the addition of Verzenio to ET did not result in a clinically meaningful difference in patients reporting being bothered by treatment ....

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New frontier in the battle against cervical cancer

Editorial Article: PARP inhibitors: A new frontier in the battle against cervical cancer
Dr. Santu Saha shares his team’s groundbreaking work to develop improved cancer treatments to avoid the potential side effects of chemotherapy
05 Feb 2021
Dr. Santu Saha, Newton International Fellow of the Academy of Medical Sciences, Newcastle University
In this exclusive interview, we hear from Dr. Santu Saha about his ongoing research into effective new ways to treat cervical cancer. Dr. Saha, a Newton International fellow of the Academy of Medical Sciences working at Newcastle University, U.K., outlines how a DNA damage response pathway inhibitor, i.e. poly(ADP-ribose) polymerase (PARP) inhibitors (PARPi), can be used to serve as reliable cancer therapies to ameliorate cisplatin toxicity whilst also targeting hypoxic tumor cells for the treatment of cervical and other cancers, where cisplatin-based chemo-radiotherapy is the standard treatment. ....

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Dr. Daniel Kopans: Will the USPSTF heed science on breast screening?

Dr. Daniel Kopans.
The history of the U.S. Preventive Services Task Force (USPSTF) on breast screening is another case in point, in which decisions on mammography guidelines have been based on flawed analyses of scientific data.
When the USPSTF last week opened a new review of breast screening guidelines, it created the opportunity to revisit the group s flawed decision in 2009 to not recommend breast screening for women in their 40s. However, a number of factors need to be addressed for the 2021 review to present a fair and impartial review of the science and evidence in favor of breast screening. ....

City Of , United Kingdom , United States , New Zealand , Ahmadr Pan , Daniel Kopans , Chiu Chen , Frodis Ewa , Canadian National Breast Screening , Wallc Canadian National Breast Screening Study , Canadian National Breast Screening Study , National Breast Screening Study Of Canada , Journal Of The National Cancer Institute Monograph , Breast Cancer Dove Med , Lennerp Service , Surveillance Modeling Network , Swedish Organised Service Screening Evaluation Group , National Evaluation Team For Breast , Canadian National Breast Screening Studies , Us Preventive Services Task , American Cancer Society , Canadian Screening Program , Us National Cancer Institute , A National Cohort Study , Norwegian Breast Cancer Screening Program , Clinical Preventive Service ,

Differences in Right vs Left Colon in Black vs White Individuals

Differences in Right vs Left Colon in Black vs White Individuals
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

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