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Prion diseases: new clues in the structure of prion proteins

A new study carried out by SISSA - Scuola Internazionale Superiore di Studi
Avanzati in collaboration with other institutions including Genos Glycoscience.
Research Laboratory from Zagreb, Croatia and Elettra Sincrotrone Trieste,
provides important information on the differences in structures of the prions, proteins responsible for diseases that at the state of the art are incurable. ....

Giuseppe Legname , Natali Naki , Scuola Internazionale Superiore , Genos Glycoscience Research Laboratory , Prion Biology Laboratory , Bovine Spongiform Encephalopathy , Creutzfeldt Jakob Disease , Internazionale Superiore , Studi Avanzati , Elettra Sincrotrone Trieste , Biology Laboratory , Medicine Health , Infectious Emerging Diseases , நடாலி னாகி , கிரெகோட்ஸ்பில்டட் ஜாகோப் நோய் , உயிரியல் ஆய்வகம் , உயிரி தொழில்நுட்பவியல் , மருந்து ஆரோக்கியம் , தொற்று வளர்ந்து வருகிறது நோய்கள் ,

Making sense of mass data generated from firing neurons

Making sense of the mass data generated from firing neurons
Dr Miguel Aguilera
Scientists have achieved a breakthrough in predicting the behaviour of neurons in large networks operating at the mysterious edge of chaos.
New research from the University of Sussex and Kyoto University outlines a new method capable of analysing the masses of data generated by thousands of individual neurons.
The new framework outperforms previous models in predicting and assessing network properties by more accurately estimating a system’s fluctuations with greater sensitivity to parameter changes.
As new technologies allow recording of thousands of neurons from living animals, there is a pressing demand for mathematical tools to study the non-equilibrium, complex dynamics of the high-dimensional data sets they generate. In this endeavour, the researchers hope to help answer key questions about how animals process information and adapt to environment ....

S Amin Moosavi , Hideaki Shimazaki , Marie Sklodowska Curie , Miguel Aguilera , School Of Engineering , Nature Communications , University Of Sussex , School Of Informatics At Kyoto University , Kyoto University , Graduate School , Associate Professor , Environmental Change , Machine Learning , Carbon Footprint , Virtual Reality , Research Fellow , Nervous System , Data Analysis , கள் அமின் மூசவி , மேரி சகிலோதோவ்ஸ்க் கியூரி , பள்ளி ஆஃப் பொறியியல் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் சசெக்ஸ் , பள்ளி ஆஃப் தகவல் இல் கியோட்டோ பல்கலைக்கழகம் , கியோட்டோ பல்கலைக்கழகம் , பட்டதாரி பள்ளி ,

New EBRAINS-enabled tool to help guide surgery in drug-resistant epilepsy patients

Credit: HBP
Epilepsy is one of the most common neurological disorders, affecting over 50 Million people worldwide. Patients suffer from seizures caused by sudden neuronal activity engaging at times large networks of the brain. In a third of all cases the disease is resistant to drugs. The most common treatment option for these patients is surgical removal of the epileptogenic zone , the areas of the brain, where the seizures emerge.
Surgery success depends on locating these areas as precisely as possible. But in clinical practice this often proves very difficult, and the average surgery success rate remains at only around 60% , says Viktor Jirsa. Any improvement would have major impact for many patients . ....

Fabrice Bartolomei , Viktor Jirsa , Pawel Swieboda , Katrin Amunts , Scientific Research , Centre National De La Recherche Scientifique , European Union , Marseille University , Research Infrastructure , Virtual Brain , Scientific Research Director , Director General , Human Brain Project , Brain Modeling , Virtual Brain Modelling , Aix Marseille University , Inserm Institut De Neurosciences Des Syst , Francois Erbsmann Prize , Early Career Distinguished Scholar Award , Grand Prix De Recherche , Scientific Director , Health Care , Medicine Health , Clinical Trials , துணி பார்டோலோமி , விக்டர் ஜீற்சா ,

How the brain processes sign language

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The ability to speak is one of the essential characteristics that distinguishes humans from other animals. Many people would probably intuitively equate speech and language. However, cognitive science research on sign languages since the 1960s paints a different picture: Today it is clear, sign languages are fully autonomous languages and have a complex organization on several linguistic levels such as grammar and meaning. Previous studies on the processing of sign language in the human brain had already found some similarities and also differences between sign languages and spoken languages. Until now, however, it has been difficult to derive a consistent picture of how both forms of language are processed in the brain. ....

Patrickc Trettenbrein , Emiliano Zaccarella , Department Of Neuropsychology , Human Brain Mapping , Health Care , Hearing Speech , Language Linguistics Speech , Learning Literacy Reading , துறை ஆஃப் நரம்பியல் உளவியல் , மனிதன் மூளை விவரணையாக்கம் , ஆரோக்கியம் பராமரிப்பு , கேட்டல் பேச்சு , மொழி மொழியியல் பேச்சு , கற்றல் கல்வியறிவு ரீடிஂக் ,

Key Decision Point for Brain Development Identified

Mouse brain showing genetically modified cells stuck in the neural precursor stage (red, yellow) and unable to progress to become neurons. Image credit:. ....

Ralitsa Petrova , Gerald Crabtree , Simon Braun , Stem Cell Research , Kavli Institute For Fundamental Neuroscience , Edyth Broad Center , Stanford University School Of Medicine , Department Of Biochemistry , Panagiotakos Lab , Howard Hughes Medical Institute , Georgia Panagiotakos , Sandler Faculty Fellow , Stanford University School , Fundamental Neuroscience , Regeneration Medicine , Stem Cell , University Of California , Stanford University , Intellectual Disability , Developmental Biology , Embryonic Development , Cell Nucleus , Cell Biology , ஜெரால்ட் நண்டு , சிமோன் மூளை , தண்டு செல் ஆராய்ச்சி ,