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Study reveals neurons responsible for rapidly stopping behaviors, actions

Credit: Cedars-Sinai
LOS ANGELES (Feb. 3, 2021) For the first time in humans, investigators at Cedars-Sinai have identified the neurons responsible for canceling planned behaviors or actions a highly adaptive skill that when lost, can lead to unwanted movements.
Known as stop signal neurons, these neurons are critical in powering someone to stop or abort an action they have already put in process.
We have all had the experience of sitting at a traffic stop and starting to press the gas pedal but then realizing that the light is still red and quickly pressing the brake again, said Ueli Rutishauser, PhD, professor of Neurosurgery, Neurology and Biomedical Sciences at Cedars-Sinai and senior author of the study published online in the peer-reviewed journal ....

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Scientists unravel the workings of a mysterious protein implicated in movement disorders

Scientists unravel the workings of a mysterious protein implicated in movement disorders
Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders.
The findings, which appear in
Cell Reports, are an advance in the basic understanding of how the brain controls muscles and could lead to treatments for children born with Gαo-mutation movement disorders. Such conditions known as GNAO1-related neurodevelopmental disorders were discovered only in the past decade, and are thought to affect at least hundreds of children around the world. Children with the disease suffer from severe developmental delays, seizures and uncontrolled muscle movements. ....

United States , Brian Muntean , Kirill Martemyanov , Emily Henderson , Scripps Research , Bow Foundation , Department Of Neuroscience , Scientists At Scripps Research , Cell Reports , Study Senior Author , Virginia Based Bow Foundation , Movement Disorders , Nervous System , ஒன்றுபட்டது மாநிலங்களில் , பிரையன் மூண்டென் , எமிலி ஹென்டர்சன் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , வில் அடித்தளம் , துறை ஆஃப் நரம்பியல் , விஞ்ஞானிகள் இல் ஸ்கிரிப்ட்கள் ஆராய்ச்சி , செல் அறிக்கைகள் , படிப்பு மூத்தவர் நூலாசிரியர் , வர்ஜீனியா அடிப்படையிலானது வில் அடித்தளம் , இயக்கம் கோளாறுகள் , பதட்டமாக அமைப்பு ,

Caltech Dedicates a Neuroscience Research Hub

Neuroscience has a new home. On Friday, January 29, Caltech hosted a virtual dedication for The Tianqiao and Chrissy Chen Neuroscience Research Building. ....

Thomasf Rosenbaum , Chrissy Luo , Richard Andersen , Davidj Anderson , Jamesg Boswell , Williamk Bowes Jr , Tianqiao Chen , David Anderson , Victor Gordo , Richard Murray , Chrissy Chen Institute For Neuroscience At Caltech , Chrissy Chen Neuroscience Research Building , Machine Interface Center Leadership , Chrissy Chen Institute For Neuroscience Leadership , Division Of Biology , Chen Institute For Neuroscience , Chen Institute Laboratory , Chen Neuroscience Research Building , Chrissy Chen Research Institute , Chen Institute , Seymour Benzer Professor , Chrissy Chen Institute , Neuroscience Leadership Chair , Most Caltech , Biological Engineering , William Davidow Presidential Chair ,

NYUAD researchers propose programming to support adolescent mothers in areas of conflict

Credit: NYU/NYU Abu Dhabi Global TIES for Children
Abu Dhabi, UAE, February 2, 2021: Adolescent mothers often fall through the cracks of educational programming. This is highly problematic given that globally an estimated 12 million girls between the ages of 15-19, and 777,000 girls under the age of 15, give birth each year. In populations affected by conflict and displacement, adolescent girls have an increased likelihood of becoming mothers due to various factors, such as disruptions to schooling, the loss of family members, poverty, gender-based violence, and poor access to healthcare and sexual and reproductive services and resources. There is a lack of support programs for these young mothers, and a continuing need for educational programming. ....

New York , United States , Abu Dhabi , Abuz Aby , United Arab Emirates , Alicej Wuermli , Hirokazu Yoshikawa , Pauld Hastings , University Of California Davis , Abu Dhabi Research Institute , Institute Of Human Development , Bioecocultural Approach , Young Children , Conflict Affected Contexts , California Davis , Human Development , Social Change , Dhabi Research Institute , Developmental Reproductive Biology , Policy Ethics , Social Behavioral Science , Learning Literacy Reading , Mental Health , Stress Anxiety , Parenting Child Care Family , Support Networks ,

Researchers Demonstrate How Defects in Mitochondria May Lead to Autism Spectrum Disorder

Date Time
Researchers Demonstrate How Defects in Mitochondria May Lead to Autism Spectrum Disorder
Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells. The findings were published online by the Proceedings of the National Academy of Sciences.
Multiple studies have revealed hundreds of mutations associated with autism spectrum disorder, but there is no consensus as to how these genetic changes cause the condition. Biochemical and physiological analyses have suggested that deficiencies in mitochondria, the “batteries” of the cell that produce most of the body’s energy, might be a possible cause. Recent studies have shown that variants of mitochondrial DNA (mtDNA) are associated with autism spectrum disorder. ....

United States , University Of Pennsylvania , Douglasc Wallace , Us Department Of Defense , Division Of Child Neurology , Developmental Disabilities Research Center , Proceedings Of The National Academy Sciences , National Institutes Of Health , Accure Inc , National Academy , Epigenomic Medicine , Charles Barnett Endowed Chair , Pediatric Mitochondrial Medicine , Metabolic Diseases , Child Neurology , Tal Yardeni , Neurobehavior Testing Core , National Institutes , Children 039s Hospital Of Philadelphia , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , எங்களுக்கு துறை ஆஃப் பாதுகாப்பு , பிரிவு ஆஃப் குழந்தை நரம்பியல் , வளர்ச்சி குறைபாடுகள் ஆராய்ச்சி மையம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , தேசிய கலைக்கழகம் ,