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Innovative corona test offers great potential for systematic testing


Innovative corona test offers great potential for systematic testing
A new corona test developed at the University Hospital Bonn can analyze a large number of swabs simultaneously using sequencing technology and has a similarly high sensitivity as the common qPCR test. The innovative method offers great potential, especially for systematic testing in daycare centers, schools or companies. Today, the results of the study on the new Corona test have been published in the renowned journal
Nature Biotechnology .
In addition to vaccination, systematic testing of the population remains of central importance in order to effectively monitor and contain the spread of infections during the Coronavirus pandemic. Only in this way can the spread of the virus be effectively monitored and contained through targeted measures. ....

Nordrhein Westfalen , Wolfgang Holzgreve , Bundesweites Forschungsnetz Angewandte , Kerstin Ludwig , Emily Henderson , Jonathan Schmid Burgk , Broad Institute , German Federal Ministry Of Education , Institute Of Human Genetics , University Hospital Bonn , Public Health , University Of Bonn , Institute Of Clinical Chemistry , Institute Of Hygiene , Clinical Chemistry , Clinical Pharmacology , Life Brain Gmbh , Bundeswehr Central Hospital Koblenz , Medical Director , German Federal Ministry , Forschungsnetz Angewandte Surveillance , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , எமிலி ஹென்டர்சன் , ஜொனாதன் ஸ்கிமிட் பர்க் , பரந்த நிறுவனம் , ஜெர்மன் கூட்டாட்சியின் அமைச்சகம் ஆஃப் கல்வி ,

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases


Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases
Autoimmune diseases, in which the body s own immune system attacks healthy tissue, can be life-threatening and can impact all organs. A research team at the Technical University of Munich (TUM) has now found a possible cause for these self-destructive immune system attacks: a hyperactive RANK protein on the surface of B cells. The research opens the door to new therapeutic possibilities.
The immune system can be a mixed blessing: Usually it is highly effective in protecting the human organism against bacteria, viruses and mycosis and even cancer. But these defense cells can also turn against the body s own tissues and trigger autoimmune diseases, including for example rheumatoid arthritis and systemic lupus erythematosus, an illness involving chronic dermatitis and inflammation of the joints, the nervous system and internal organs or even become cancer cells themselves and dev ....

Maike Buchner , Juergen Ruland , Emily Henderson , Technical University Of Munich , German Research Foundation , Institute Of Clinical Chemistry , Institute For Clinical Chemistry , Technical University , Clinical Chemistry , Research Foundation , Leibniz Prize , Receptor Activator , Autoimmune Disease , Immune System , Lupus Erythematosus , Nervous System , Rheumatoid Arthritis , Systemic Lupus Erythematosus , ஜூர்கன் ருளந்ட் , எமிலி ஹென்டர்சன் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , நிறுவனம் ஆஃப் மருத்துவ வேதியியல் , நிறுவனம் க்கு மருத்துவ வேதியியல் , தொழில்நுட்ப பல்கலைக்கழகம் , மருத்துவ வேதியியல் ,

When hyperactive proteins trigger illnesses


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The immune system can be a mixed blessing: Usually it is highly effective in protecting the human organism against bacteria, viruses and mycosis and even cancer. But these defense cells can also turn against the body s own tissues and trigger autoimmune diseases, including for example rheumatoid arthritis and systemic lupus erythematosus, an illness involving chronic dermatitis and inflammation of the joints, the nervous system and internal organs or even become cancer cells themselves and develop into leukemias or lymphomas. But what causes these destructive immune system attacks?
The question has yet to be finally resolved, says Prof. Juergen Ruland, Director of the TUM Institute for Clinical Chemistry and Pathobiochemistry. B cells, a subgroup of white blood corpuscles produced in the bone marrow, play a central role in regulating immune responses. During a normal immune response, activated B cells produce antibodies which attack foreign substances. Defectiv ....

Maike Buchner , Juergen Ruland , German Research Foundation , Institute Of Clinical Chemistry , Institute For Clinical Chemistry , Clinical Chemistry , Research Foundation , Leibniz Prize , Receptor Activator , ஜூர்கன் ருளந்ட் , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , நிறுவனம் ஆஃப் மருத்துவ வேதியியல் , நிறுவனம் க்கு மருத்துவ வேதியியல் , மருத்துவ வேதியியல் , ஆராய்ச்சி அடித்தளம் , ஏற்பி ஆக்டிவேட்டர் ,